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Reorganization characteristics of speech cortex during speech restoration following total laryngectomy. A functional magnetic resonance imaging follow-up

文献类型：期刊论文

作者Yin, Jianzhong1; Xue, Yonggang1; Lin, Peng2; Weng, Xuchu3; Qi, Ji1
刊名NEURAL REGENERATION RESEARCH
出版日期2011-04-15
卷号6期号:11页码:834-838
关键词magnetic resonance imaging functional laryngeal carcinoma laryngectomy language training neuroplasticity
ISSN号1673-5374
产权排序3
通讯作者Yin, JZ (reprint author), Tianjin Med Univ, Cent Clin Coll 1, Tianjin Cent Hosp 1, Dept Radiol, Tianjin 300192, Peoples R China.
英文摘要During speech restoration following laryngectomy, language-related cortical areas develop connections with new primary motor neurons. The present study followed up 18 patients after total resection of laryngeal carcinoma. According to an evaluation of pronunciation, patients were assigned to three groups: poor, moderate and good pronunciation. Functional magnetic resonance imaging revealed significant increases in the number of activated voxels and the intensity of activation changes in the left middle frontal gyrus, left precentral gyrus, left postcentral gyrus, left supplementary motor area, left anterior cingulate gyrus and right fusiform gyrus between the moderate pronunciation group compared with the poor and good pronunciation groups. We propose that these brain regions play an important role in the progress of speech restoration, and improvements in pronunciation learning for patients following laryngectomy. However, during the later period of speech restoration, the number of activated voxels and intensity changes in these regions decreased to the level of healthy controls, indicating that the learning and instruction effects weakened once patients had mastered pronunciation techniques.
学科主题Medical psychology
收录类别SCI
项目简介The study was supported by the Natural Science Foundation of Tianjin, No. 06YFJMJC09300.
原文出处http://www.cnki.com.cn/Article/CJFDTOTAL-SJZY201111010.htm
语种英语
WOS记录号WOS:000291416100007
源URL[http://ir.psych.ac.cn/handle/311026/13241]  
专题心理研究所_中国科学院心理健康重点实验室
作者单位1.Tianjin Med Univ, Cent Clin Coll 1, Tianjin Cent Hosp 1, Dept Radiol, Tianjin 300192, Peoples R China
2.Tianjin Med Univ, Cent Clin Coll 1, Tianjin Cent Hosp 1, Dept Otolaryngol, Tianjin 300192, Peoples R China
3.Chinese Acad Sci, Inst Psychol, Beijing 100101, Peoples R China
推荐引用方式
GB/T 7714		 Yin, Jianzhong,Xue, Yonggang,Lin, Peng,et al. Reorganization characteristics of speech cortex during speech restoration following total laryngectomy. A functional magnetic resonance imaging follow-up[J]. NEURAL REGENERATION RESEARCH,2011,6(11):834-838.
APA Yin, Jianzhong,Xue, Yonggang,Lin, Peng,Weng, Xuchu,&Qi, Ji.(2011).Reorganization characteristics of speech cortex during speech restoration following total laryngectomy. A functional magnetic resonance imaging follow-up.NEURAL REGENERATION RESEARCH,6(11),834-838.
MLA Yin, Jianzhong,et al."Reorganization characteristics of speech cortex during speech restoration following total laryngectomy. A functional magnetic resonance imaging follow-up".NEURAL REGENERATION RESEARCH 6.11(2011):834-838.

入库方式： OAI收割

来源：心理研究所

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