Detection and Quantification of DNA Adducts
文献类型：期刊论文
| 作者 | Feng Feng ; Wang Chao ; Lue Meiling ; Wang Hailin |
| 刊名 | PROGRESS IN CHEMISTRY
 |
| 出版日期 | 2009-03 |
| 卷号 | 21期号:1页码:503-513 |
| 关键词 | DNA adducts capillary electrophoresis-laser induced fluorescence (CE-LIF) (32)P-postlabelling mass spectrometry |
| 中文摘要 | DNA adducts are an important class of biomarkers for monitoring of environmental carcinogen exposure and evaluation of population susceptibility, and an indicator of cancer risk. DNA adduct analysis has been widely applied in a number of fields, including human biomonitoring of carcinogen exposure, evaluation of genotoxicity and population susceptibility, carcinogen-gene interactions, cancer risk assessment, screening of carcinogenic environmental factors, cancer prevention. The reliable, sensitive and accurate detection and identification of DNA adducts is a key to the wide application of DNA adducts as biomarkers. A number of techniques and methods have been developed for the detection of DNA adducts, such as (32)P-postlabelling, immunoassay, immuno-CE/LIF, LC/MS, micro-scale separation coupled MS. Applications of these techniques as well as related future development are briefly reviewed and discussed in this article. |
| WOS记录号 | WOS:000264790400023 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/21478]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Feng Feng,Wang Chao,Lue Meiling,et al. Detection and Quantification of DNA Adducts[J]. PROGRESS IN CHEMISTRY,2009,21(1):503-513. |
| APA | Feng Feng,Wang Chao,Lue Meiling,&Wang Hailin.(2009).Detection and Quantification of DNA Adducts.PROGRESS IN CHEMISTRY,21(1),503-513. |
| MLA | Feng Feng,et al."Detection and Quantification of DNA Adducts".PROGRESS IN CHEMISTRY 21.1(2009):503-513. |
入库方式： OAI收割
来源：生态环境研究中心
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