The first chemical synthesis of F-4-GlcA beta(1 -> 3)GlcNAc-UDP with the potential of novel substrate and enzyme inhibitor for hyaluronic acid synthases (HASs)
文献类型：期刊论文
| 作者 | Wei, Guohua; Kumar, Vipin; Xue, Jun; Locke, Robert D.; Matta, Khushi L. |
| 刊名 | TETRAHEDRON LETTERS
 |
| 出版日期 | 2009-10-28 |
| 卷号 | 50期号:43页码:5920-5922 |
| 关键词 | F-4-GlcA Hyaluronic acid synthases (HASs) Oligosaccharides Phosphates |
| 中文摘要 | The first chemical synthesis of F-4-GlcA beta(1 -> 3)GlcNAc-UDP is described here. This compound can serve as a novel substrate to study the catalytic mechanism of hyaluronic acid synthases (HASs) and has potential to be donor for these enzymes that extend HA chain at the reducing end. Moreover, it may also behave as inhibitor for the enzymes that act on non-reducing end in the assembly of HA chain. (C) 2009 Elsevier Ltd. All rights reserved. |
| WOS记录号 | WOS:000270421700011 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/21577]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Wei, Guohua,Kumar, Vipin,Xue, Jun,et al. The first chemical synthesis of F-4-GlcA beta(1 -> 3)GlcNAc-UDP with the potential of novel substrate and enzyme inhibitor for hyaluronic acid synthases (HASs)[J]. TETRAHEDRON LETTERS,2009,50(43):5920-5922. |
| APA | Wei, Guohua,Kumar, Vipin,Xue, Jun,Locke, Robert D.,&Matta, Khushi L..(2009).The first chemical synthesis of F-4-GlcA beta(1 -> 3)GlcNAc-UDP with the potential of novel substrate and enzyme inhibitor for hyaluronic acid synthases (HASs).TETRAHEDRON LETTERS,50(43),5920-5922. |
| MLA | Wei, Guohua,et al."The first chemical synthesis of F-4-GlcA beta(1 -> 3)GlcNAc-UDP with the potential of novel substrate and enzyme inhibitor for hyaluronic acid synthases (HASs)".TETRAHEDRON LETTERS 50.43(2009):5920-5922. |
入库方式： OAI收割
来源：生态环境研究中心
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