Effect of polybrominated diphenyl ether on development of cultured hippocampal neuron
文献类型：期刊论文
| 作者 | Liao ChunYang; Duan ShuMin; Jiang GuiBin |
| 刊名 | SCIENCE IN CHINA SERIES B-CHEMISTRY
 |
| 出版日期 | 2008-01 |
| 卷号 | 51期号:1页码:62-68 |
| 关键词 | polybrominated diphenyl ether (PBDE) neuron neurite synapse development inhibition |
| 英文摘要 | Polybrominated diphenyl ether (PBDE) is a persistently environmental pollutant ubiquitously found in wildlife and humans. Although concern on PBDE's toxic effects is steadily increasing, its action on the central nervous system (CNS) remains largely unknown. To address this issue, the present study examined the development inhibition of PBDE in neurons. The primary cultured hippocampal neurons of rat were exposed to the commercial decabromodiphenyl ether (deca-BDE), and the neurite length, bifurcation, and synapse formation and maturation were evaluated, based on the confocal microscope imaging. The results showed that the development inhibition in neurons occurred at 15 mu mol/L, indicating that PBDE is a potent neurotoxicant and it might obviously inhibit the development of cultured neurons. |
| WOS记录号 | WOS:000251972200010 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/21940]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Liao ChunYang,Duan ShuMin,Jiang GuiBin. Effect of polybrominated diphenyl ether on development of cultured hippocampal neuron[J]. SCIENCE IN CHINA SERIES B-CHEMISTRY,2008,51(1):62-68. |
| APA | Liao ChunYang,Duan ShuMin,&Jiang GuiBin.(2008).Effect of polybrominated diphenyl ether on development of cultured hippocampal neuron.SCIENCE IN CHINA SERIES B-CHEMISTRY,51(1),62-68. |
| MLA | Liao ChunYang,et al."Effect of polybrominated diphenyl ether on development of cultured hippocampal neuron".SCIENCE IN CHINA SERIES B-CHEMISTRY 51.1(2008):62-68. |
入库方式： OAI收割
来源：生态环境研究中心
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。