On-line sample treatment LC system for MS compatibility
文献类型：期刊论文
| 作者 | Hashi, Yuki ; Yao, Jian-Guo ; Li, Yue-Qi ; Liu, Yan ; Lin, Jin-Ming |
| 刊名 | CHROMATOGRAPHIA
 |
| 出版日期 | 2008-05 |
| 卷号 | 67期号:1页码:773-776 |
| 关键词 | column liquid chromatography-mass spectrometry on-line sample pretreatment natural products coptidis Rhizoma |
| 英文摘要 | In the present work, a new liquid chromatography-mass spectrometry (LC-MS) system with on-line pretreatment using column switching and a dilution function was developed. This system can be used under conventional high-performance liquid chromatography (LC) separation conditions, including mobile phases containing phosphate buffer. The built-in autodilution function greatly improves the trapping efficiency for target compounds, followed by desaltation that optimizes the ionization conditions for MS analysis. This fully automated two-dimensional LC system interfaced with mass spectrometry provided a powerful tool for the determination of impurity profiles in pharmaceutical research and the identification of traditional Chinese medicine in natural products. |
| WOS记录号 | WOS:000255751100016 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/21967]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Hashi, Yuki,Yao, Jian-Guo,Li, Yue-Qi,et al. On-line sample treatment LC system for MS compatibility[J]. CHROMATOGRAPHIA,2008,67(1):773-776. |
| APA | Hashi, Yuki,Yao, Jian-Guo,Li, Yue-Qi,Liu, Yan,&Lin, Jin-Ming.(2008).On-line sample treatment LC system for MS compatibility.CHROMATOGRAPHIA,67(1),773-776. |
| MLA | Hashi, Yuki,et al."On-line sample treatment LC system for MS compatibility".CHROMATOGRAPHIA 67.1(2008):773-776. |
入库方式： OAI收割
来源：生态环境研究中心
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