中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Comparison of ethinylestradiol and nonylphenol effects on reproduction of Chinese rare minnows (Gobiocypris rarus)

文献类型:期刊论文

作者Zha, Jinmiao ; Sun, Liwei ; Spear, Philip A. ; Wang, Zijian
刊名ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
出版日期2008-10
卷号71期号:2页码:390-399
关键词Gobiocypris rarus vitellogenin histopathology reproduction 17 alpha-ethinylestradiol 4-nonylphenol
英文摘要Breeding pairs of rare minnows were exposed to 5, 10, 20 mu g/L 4-nonylphenol (NP) or 4 ng/L 17 alpha-ethinylestradiol (EE2) for 21 days. Among reproductive parameters investigated, fecundity, fertility, and laying interval were significantly affected by 4 ng/L EE2, but were not affected at any exposure level of NP. These effects coincided with male feminization, ova-testis, increased plasma VTG in both males and females as well as the accumulation of eosinophilic material in kidneys and livers. Histopathologic evaluation revealed severe kidney lesions in both EE2 and NP-exposed fish. The bioassay succeeded in demonstrating that EE2 was several orders of magnitude more potent than the industrial chemical NP. The rare minnow was more sensitive to EE2 than medaka, but comparable to zebrafish in terms of sensitivity. The results of the present investigation indicated that a short-term reproductive bioassay is feasible using the Chinese rare minnow as the test species. (c) 2007 Elsevier Inc. All rights reserved.
WOS记录号WOS:000259713900009
源URL[http://ir.rcees.ac.cn/handle/311016/22222]  
专题生态环境研究中心_环境水质学国家重点实验室
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Zha, Jinmiao,Sun, Liwei,Spear, Philip A.,et al. Comparison of ethinylestradiol and nonylphenol effects on reproduction of Chinese rare minnows (Gobiocypris rarus)[J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,2008,71(2):390-399.
APA Zha, Jinmiao,Sun, Liwei,Spear, Philip A.,&Wang, Zijian.(2008).Comparison of ethinylestradiol and nonylphenol effects on reproduction of Chinese rare minnows (Gobiocypris rarus).ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,71(2),390-399.
MLA Zha, Jinmiao,et al."Comparison of ethinylestradiol and nonylphenol effects on reproduction of Chinese rare minnows (Gobiocypris rarus)".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 71.2(2008):390-399.

入库方式: OAI收割

来源:生态环境研究中心

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