中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Gender consistency and difference in healthy adults revealed by cortical thickness

文献类型:期刊论文

作者Lv, Bin1; Li, Jing2; He, Huiguang1; Li, Meng1; Zhao, Mingchang1; Ai, Likun3; Yan, Fei2; Xian, Junfang2; Wang, Zhenchang2
刊名NEUROIMAGE
出版日期2010-11-01
卷号53期号:2页码:373-382
关键词Gender consistency Gender difference Cortical thickness Anatomical correlation
英文摘要Many previous studies have shown that there exists the gender effect on the structural and functional organization in the human brain Although the reported functional differences are generally consistent, the structural differences are controversial among the various studies. In this study, we particularly focused on the gender-related effect in the gray matter (GM) We performed a structural magnetic resonance imaging (MRI) study in 184 healthy adults (90 males and 94 females) with ages ranging from 18 to 70 years Cortical thickness was measured using an automated surface-based method Based on this surface morphological feature of GM, we first compared their regional differences between males and females We then constructed the morphometry-based anatomical networks derived from cortical thickness measurement, while the anatomical connection between two cortical areas depended upon the statistical dependence of their cortical thickness across subjects Subsequently, we applied graph theoretical approaches to investigate the properties of the resultant anatomical networks The results showed that the significant gender-related differences of cortical thickness appeared extensively in the frontal, parietal and occipital lobes. And there were also some between-group differences in the interregional correlation. Additional graph theoretical analysis on the morphological networks revealed both networks exhibited the small-world efficiency and their patterns of topological vulnerability had no statistical differences The findings on the large sample may provide the evidences to study the gender consistency and difference in the human brain structures. (C) 2010 Published by Elsevier Inc.
WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Neurosciences ; Neuroimaging ; Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]Neurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]AUTOMATED 3-D EXTRACTION ; COMPLEX BRAIN NETWORKS ; SMALL-WORLD ; CEREBRAL-CORTEX ; SEX-DIFFERENCES ; FUNCTIONAL-ORGANIZATION ; MULTIPLE-SCLEROSIS ; MRI DATA ; VOLUME ; SCHIZOPHRENIA
收录类别SCI
语种英语
WOS记录号WOS:000281688000002
源URL[http://ir.ia.ac.cn/handle/173211/3733]  
专题自动化研究所_复杂系统管理与控制国家重点实验室_影像分析与机器视觉团队
作者单位1.Chinese Acad Sci, Inst Automat, Key Lab Complex Syst & Intelligence Sci, Beijing 100190, Peoples R China
2.Capital Med Univ, Beijing Tongren Hosp, Dept Radiol, Beijing, Peoples R China
3.Capital Med Univ, Beijing Tongren Hosp, Ctr Eye, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Lv, Bin,Li, Jing,He, Huiguang,et al. Gender consistency and difference in healthy adults revealed by cortical thickness[J]. NEUROIMAGE,2010,53(2):373-382.
APA Lv, Bin.,Li, Jing.,He, Huiguang.,Li, Meng.,Zhao, Mingchang.,...&Wang, Zhenchang.(2010).Gender consistency and difference in healthy adults revealed by cortical thickness.NEUROIMAGE,53(2),373-382.
MLA Lv, Bin,et al."Gender consistency and difference in healthy adults revealed by cortical thickness".NEUROIMAGE 53.2(2010):373-382.

入库方式: OAI收割

来源:自动化研究所

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