Altered Resting-State Network Connectivity in Congenital Blind
文献类型：期刊论文
| 作者 | Wang, Dawei1,2; Qin, Wen1,2; Liu, Yong3 ; Zhang, Yunting1,2; Jiang, Tianzi3; Yu, Chunshui1,2,4
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| 刊名 | HUMAN BRAIN MAPPING
 |
| 出版日期 | 2014-06-01 |
| 卷号 | 35期号:6页码:2573-2581 |
| 关键词 | congenital blind resting-state network MRI independent component analysis |
| 英文摘要 | The brain of congenital blind (CB) has experienced a series of structural and functional alterations, either undesirable outcomes such as atrophy of the visual pathway due to sight loss from birth, or compensatory plasticity to interact efficiently with the environment. However, little is known, so far, about alterations in the functional architecture of resting-state networks (RSNs) in CB. This study aimed to investigate intra- and internetwork connectivity differences between CB and sighted controls (SC), using independent component analysis (ICA) on resting state functional MRI data. Compared with SC, CB showed significantly increased network connectivity within the salience network (SN) and the occipital cortex. Moreover, CB exhibited enhanced internetwork connectivity between the SN and the frontoparietal network (FPN) and between the FPN and the occipital cortex; however, they showed decreased internetwork connectivity between the occipital cortex and the sensorimotor network. These findings suggest that CB experience large scale reorganization at the level of the functional network. More importantly, the enhanced intra- and internetwork connectivity of the SN, FPN, and occipital cortex in CB may improve their abilities to identify salient stimuli, to initiate the executive function, and to top-down control of attention, which are critical for the CB to guide appropriate behavior and to better adaption to the environment. Hum Brain Mapp 35:2573-2581, 2014. (c) 2013 Wiley Periodicals, Inc. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Neurosciences ; Neuroimaging ; Radiology, Nuclear Medicine & Medical Imaging |
| 研究领域[WOS] | Neurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging |
| 关键词[WOS] | INDEPENDENT COMPONENT ANALYSIS ; VISUAL-CORTEX ACTIVATION ; CEREBRAL-BLOOD-FLOW ; FUNCTIONAL CONNECTIVITY ; HUMAN BRAIN ; DEFAULT-MODE ; OCCIPITAL CORTEX ; WORKING-MEMORY ; PREFRONTAL CORTEX ; WHITE-MATTER |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000334555100007 |
| 源URL | [http://ir.ia.ac.cn/handle/173211/3148]  |
| 专题 | 自动化研究所_脑网络组研究中心 |
| 作者单位 | 1.Tianjin Med Univ, Dept Radiol, Gen Hosp, Tianjin 300052, Peoples R China 2.Tianjin Med Univ, Tianjin Key Lab Funct Imaging, Gen Hosp, Tianjin 300052, Peoples R China 3.Chinese Acad Sci, Brainnetome Ctr, Natl Lab Pattern Recognit, Inst Automat, Beijing 100190, Peoples R China 4.Tianjin Med Univ, Sch Med Imaging, Tianjin 300052, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Dawei,Qin, Wen,Liu, Yong,et al. Altered Resting-State Network Connectivity in Congenital Blind[J]. HUMAN BRAIN MAPPING,2014,35(6):2573-2581. |
| APA | Wang, Dawei,Qin, Wen,Liu, Yong,Zhang, Yunting,Jiang, Tianzi,&Yu, Chunshui.(2014).Altered Resting-State Network Connectivity in Congenital Blind.HUMAN BRAIN MAPPING,35(6),2573-2581. |
| MLA | Wang, Dawei,et al."Altered Resting-State Network Connectivity in Congenital Blind".HUMAN BRAIN MAPPING 35.6(2014):2573-2581. |
入库方式： OAI收割
来源：自动化研究所
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