Connectivity-Based Parcellation of the Human Frontal Pole with Diffusion Tensor Imaging
文献类型：期刊论文
| 作者 | Liu, Huaigui1; Qin, Wen1; Li, Wei1 ; Fan, Lingzhong2; Wang, Jiaojian3; Jiang, Tianzi2; Yu, Chunshui1
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| 刊名 | JOURNAL OF NEUROSCIENCE
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| 出版日期 | 2013-04-17 |
| 卷号 | 33期号:16页码:6782-6790 |
| 英文摘要 | The human frontal pole (FP) approximately corresponds to Brodmann's area 10 and is a highly differentiated cortical area with unique cytoarchitectonic characteristics. However, its functional diversity is highly suggestive of the existence of functional subregions. Based on anatomical connection patterns derived from diffusion tensor imaging data, we applied a spectral clustering algorithm to parcellate the human right FP into orbital (FPo), lateral (FPl), and medial (FPm) subregions. This parcellation scheme was validated by corresponding analyses of the left FP and right FP in another independent dataset. Both visual observation and quantitative comparison of the anatomical connection patterns of the three FP subregions revealed that the FPo showed greater connection probabilities to brain regions of the social emotion network (SEN), including the orbitofrontal cortex, temporal pole, and amygdala, the FPl showed stronger connections to the dorsolateral prefrontal cortex of the cognitive processing network (CPN), and the FPm showed stronger connections to brain areas of the default mode network (DMN), including the anterior cingulate cortex and medial prefrontal cortex. We further analyzed the resting-state functional connectivity patterns of the three FP subregions. Consistent with the findings of anatomical connection analyses, the FPo was functionally correlated with the SEN, the FPl was correlated with the CPN, and the FPm was correlated with the DMN. These findings suggest that the human FP includes three separable subregions with different anatomical and functional connectivity patterns and that these subregions are involved in different brain functional networks and serve different functions. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Neurosciences |
| 研究领域[WOS] | Neurosciences & Neurology |
| 关键词[WOS] | ROSTRAL PREFRONTAL CORTEX ; STATE FUNCTIONAL CONNECTIVITY ; TRACTOGRAPHY-BASED PARCELLATION ; HUMAN ORBITOFRONTAL CORTEX ; STRUCTURAL CONNECTIVITY ; ANTERIOR CINGULATE ; DECISION-MAKING ; MACAQUE MONKEYS ; PARIETAL CORTEX ; CEREBRAL-CORTEX |
| 收录类别 | SCI ; SSCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000317723000010 |
| 源URL | [http://ir.ia.ac.cn/handle/173211/3152]  |
| 专题 | 自动化研究所_脑网络组研究中心 |
| 作者单位 | 1.Tianjin Med Univ, Gen Hosp, Dept Radiol, Tianjin 300052, Peoples R China 2.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Ctr Computat Med,Sinofrench Lab Comp Sci Automat, Beijing 100190, Peoples R China 3.Univ Elect Sci & Technol China, Sch Life Sci & Technol, Key Lab NeuroInformat, Minist Educ, Chengdu 625014, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Huaigui,Qin, Wen,Li, Wei,et al. Connectivity-Based Parcellation of the Human Frontal Pole with Diffusion Tensor Imaging[J]. JOURNAL OF NEUROSCIENCE,2013,33(16):6782-6790. |
| APA | Liu, Huaigui.,Qin, Wen.,Li, Wei.,Fan, Lingzhong.,Wang, Jiaojian.,...&Yu, Chunshui.(2013).Connectivity-Based Parcellation of the Human Frontal Pole with Diffusion Tensor Imaging.JOURNAL OF NEUROSCIENCE,33(16),6782-6790. |
| MLA | Liu, Huaigui,et al."Connectivity-Based Parcellation of the Human Frontal Pole with Diffusion Tensor Imaging".JOURNAL OF NEUROSCIENCE 33.16(2013):6782-6790. |
入库方式： OAI收割
来源：自动化研究所
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