Brainnetome: A new -ome to understand the brain and its disorders
文献类型：期刊论文
| 作者 | Jiang, Tianzi1,2,3,4
|
| 刊名 | NEUROIMAGE
 |
| 出版日期 | 2013-10-15 |
| 卷号 | 80页码:263-272 |
| 关键词 | Brainnetome Brain network Connectome Brain connectivity Neuroimaging |
| 英文摘要 | The human brain can be studied as a hierarchy of complex networks on different temporal and spatial scales. On each scale, from gene, protein, synapse, neuron and microcircuit, to area, pathway and the whole brain, many advances have been made with the development of related techniques. Brain network studies on different temporal and spatial scales are booming. However, such studies have focused on single levels, and can only reflect limited aspects of how the brain is formed and how it works. Therefore, it is increasingly urgent to integrate a variety of techniques, methods and models, and to merge fragmented findings into a uniform research framework or platform. To this end, we have proposed the concept of the brainnetome and several related programs/projects have been launched in China. In this paper, we offer a brief review on the methodologies of the brainnetome, which include techniques on different scales, the brainnetome atlas, and methods of brain network analysis. We then take Alzheimer's disease and schizophrenia as examples to show how the brainnetome can be studied in neurological and psychiatric disorders. We also review the studies of how risk genes for brain diseases affect the brain networks. Finally, we summarize the challenges for the brainnetome, and what actions and measures have been taken to address these challenges in China. It is envisioned that the brainnetome will open new avenues and some long-standing issues may be solved by combining the brainnetome with other "omes". (C) 2013 Elsevier Inc. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Neurosciences ; Neuroimaging ; Radiology, Nuclear Medicine & Medical Imaging |
| 研究领域[WOS] | Neurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging |
| 关键词[WOS] | RESTING-STATE FMRI ; SEROTONIN TRANSPORTER GENE ; MAJOR DEPRESSIVE DISORDER ; TRACTOGRAPHY-BASED PARCELLATION ; COGNITIVE IMPAIRMENT EVIDENCE ; EARLY ALZHEIMERS-DISEASE ; WHITE-MATTER INTEGRITY ; SMALL-WORLD NETWORKS ; FUNCTIONAL CONNECTIVITY ; ANTIDEPRESSANT RESPONSE |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000322416000020 |
| 源URL | [http://ir.ia.ac.cn/handle/173211/3159]  |
| 专题 | 自动化研究所_脑网络组研究中心 |
| 作者单位 | 1.Chinese Acad Sci, Brainnetome Ctr, Inst Automat, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100190, Peoples R China 3.Univ Elect Sci & Technol China, Sch Life Sci & Technol, Minist Educ, Key Lab NeuroInformat, Chengdu 610054, Peoples R China 4.Univ Queensland, Queensland Brain Inst, Brisbane, Qld 4072, Australia |
| 推荐引用方式 GB/T 7714 | Jiang, Tianzi. Brainnetome: A new -ome to understand the brain and its disorders[J]. NEUROIMAGE,2013,80:263-272. |
| APA | Jiang, Tianzi.(2013).Brainnetome: A new -ome to understand the brain and its disorders.NEUROIMAGE,80,263-272. |
| MLA | Jiang, Tianzi."Brainnetome: A new -ome to understand the brain and its disorders".NEUROIMAGE 80(2013):263-272. |
入库方式： OAI收割
来源：自动化研究所
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