中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
A new numerical method for BLT forward problem based on high-order finite elements

文献类型:期刊论文

作者Hou, Yanbin2; Tian, Jie1,2; Wu, Yan2; Liang, Jimin2; He, Xiaowei2
刊名COMMUNICATIONS IN NUMERICAL METHODS IN ENGINEERING
出版日期2009-06-01
卷号25期号:6页码:667-681
关键词molecular imaging bioluminescence tomography forward problem high-order finite elements diffusion approximation
英文摘要Molecular imaging possesses the ability to characterize and measure biological processes at the cellular and molecular level in vivo. As one of the new molecular imaging modalities, biolminescence tomography (BLT) is to reconstruct the light distribution inside a small animal from the photon flux measured on its surface. To obtain accurate and robust reconstruction, it needs a good understanding of the propagation of photons in biological tissues, which is referred to as the forward problem in BLT. Because the turbid media is high scattering and low absorption, the propagation process can be described by the steady diffusion equation. In this paper, an hp-adaptivity method for BLT forward problem is presented based on finite elements of high orders and moderate meshes by finite element method (FEM). Both numerical simulation and physical experiment are performed to evaluate the accuracy of solution and the efficiency of computation. The relevant results show that element order is more critical than mesh size to produce an accurate FEM solution efficiently. Copyright (C) 2008 John Wiley & Sons, Ltd.
WOS标题词Science & Technology ; Technology ; Physical Sciences
类目[WOS]Engineering, Multidisciplinary ; Mathematics, Interdisciplinary Applications
研究领域[WOS]Engineering ; Mathematics
关键词[WOS]BIOLUMINESCENCE TOMOGRAPHY ; SCATTERING MEDIA ; IN-VIVO ; LIGHT ; TRANSPORT ; RECONSTRUCTION ; PROPAGATION ; SIMULATION
收录类别SCI
语种英语
WOS记录号WOS:000267062200007
源URL[http://ir.ia.ac.cn/handle/173211/3904]  
专题自动化研究所_中国科学院分子影像重点实验室
作者单位1.Chinese Acad Sci, Inst Automat, Med Image Proc Grp, Beijing 100080, Peoples R China
2.Xidian Univ, Sch Elect Engn, Life Sci Res Ctr, Xian 710071, Shaanxi, Peoples R China
推荐引用方式
GB/T 7714
Hou, Yanbin,Tian, Jie,Wu, Yan,et al. A new numerical method for BLT forward problem based on high-order finite elements[J]. COMMUNICATIONS IN NUMERICAL METHODS IN ENGINEERING,2009,25(6):667-681.
APA Hou, Yanbin,Tian, Jie,Wu, Yan,Liang, Jimin,&He, Xiaowei.(2009).A new numerical method for BLT forward problem based on high-order finite elements.COMMUNICATIONS IN NUMERICAL METHODS IN ENGINEERING,25(6),667-681.
MLA Hou, Yanbin,et al."A new numerical method for BLT forward problem based on high-order finite elements".COMMUNICATIONS IN NUMERICAL METHODS IN ENGINEERING 25.6(2009):667-681.

入库方式: OAI收割

来源:自动化研究所

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