中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
A source reconstruction algorithm based on adaptive hp-FEM for bioluminescence tomography

文献类型:期刊论文

作者Han, Runqiang1,2; Liang, Jimin1; Qu, Xiaochao1; Hou, Yanbin1; Ren, Nunu1,2; Mao, Jingjing1,2; Tian, Jie1,2,3
刊名OPTICS EXPRESS
出版日期2009-08-17
卷号17期号:17页码:14481-14494
英文摘要As a novel modality of molecular imaging, bioluminescence tomography (BLT) is used to in vivo observe and measure the biological process at cellular and molecular level in small animals. The core issue of BLT is to determine the distribution of internal bioluminescent sources from optical measurements on external surface. In this paper, a new algorithm is presented for BLT source reconstruction based on adaptive hp-finite element method. Using adaptive mesh refinement strategy and intelligent permissible source region, we can obtain more accurate information about the location and density of sources, with the robustness, stability and efficiency improved. Numerical simulations and physical experiment were both conducted to verify the performance of the proposed algorithm, where the optical data on phantom surface were obtained via Monte Carlo simulation and CCD camera detection, respectively. The results represent the merits and potential of our algorithm for BLT source reconstruction. (C) 2009 Optical Society of America
WOS标题词Science & Technology ; Physical Sciences
类目[WOS]Optics
研究领域[WOS]Optics
关键词[WOS]FINITE-ELEMENT-METHOD ; OPTICAL-PROPERTIES ; APPROXIMATION ; LIGHT ; INFORMATION ; STRATEGY ; MEDIA
收录类别SCI
语种英语
WOS记录号WOS:000269232800003
源URL[http://ir.ia.ac.cn/handle/173211/3905]  
专题自动化研究所_中国科学院分子影像重点实验室
作者单位1.Xidian Univ, Life Sci Res Ctr, Sch Life Sci & Technol, Xian 710071, Shaanxi, Peoples R China
2.Xidian Univ, Sch Elect Engn, Xian 710071, Shaanxi, Peoples R China
3.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China
推荐引用方式
GB/T 7714
Han, Runqiang,Liang, Jimin,Qu, Xiaochao,et al. A source reconstruction algorithm based on adaptive hp-FEM for bioluminescence tomography[J]. OPTICS EXPRESS,2009,17(17):14481-14494.
APA Han, Runqiang.,Liang, Jimin.,Qu, Xiaochao.,Hou, Yanbin.,Ren, Nunu.,...&Tian, Jie.(2009).A source reconstruction algorithm based on adaptive hp-FEM for bioluminescence tomography.OPTICS EXPRESS,17(17),14481-14494.
MLA Han, Runqiang,et al."A source reconstruction algorithm based on adaptive hp-FEM for bioluminescence tomography".OPTICS EXPRESS 17.17(2009):14481-14494.

入库方式: OAI收割

来源:自动化研究所

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