Acupuncture modulates spontaneous activities in the anticorrelated resting brain networks
文献类型：期刊论文
| 作者 | Bai, Lijun2; Qin, Wei2; Tian, Jie1,2 ; Dong, Minghao2; Pan, Xiaohong5; Chen, Peng6; Dai, Jianping7; Yang, Wanhai8; Liu, Yijun3,4
|
| 刊名 | BRAIN RESEARCH
 |
| 出版日期 | 2009-07-07 |
| 卷号 | 1279页码:37-49 |
| 关键词 | Accupuncture Insula Endogenous pain modulation Spontaneous brain activity Anticorrelated resting brain network |
| 英文摘要 | Neuroimaging studies of acupuncture have demonstrated extensive signal attenuations in the core regions of a "default mode" network as well as signal potentiations in the regions of a "central-executive" network. We proposed that this acupuncture-related dichotomy may represent the anticorrelation in these intrinsic brain networks showing spontaneous fluctuations during rest. According to a plentiful clinical report, acupuncture can provide pain relief beyond the time it is being administrated; therefore, imaging its sustained effect (rather than acute effect) on the brain networks may further help elucidate the mechanisms by which acupuncture achieves its therapeutic effects. As ail interface, the anterior insula (AI) has recently been shown to be a network hub, which initiates dynamic switching between these intrinsic networks. Here, we attempt to explore how acupuncture can modulate spontaneous coherences of these resting networks anchored by the AI. Using a spontaneous activity detection approach, we identified an AI-related dichotomy showing spontaneous activations in the CEN along with wide spontaneous deactivations located exclusively in the DMN. Following verum acupuncture, but not sham control, there was a prominently enhanced dichotomy in the CEN and DMN networks. More importantly, a long-lasting effect of acupuncture could further modulate intrinsic coherences of the wide interoceptive-autonomic areas, including the paralimbic regions and brainstem nuclei. These findings suggested that acupuncture may not only enhance the dichotomy of the anticorrelated resting networks, but also modulate a larger spatio-temporal extent of spontaneous activities in the salient interoceptive-autonomic network, contributing to potential actions in the endogenous pain-modulation circuits and homeostatic control mechanisms. Crown Copyright (C) 2009 Published by Elsevier B.V. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Neurosciences |
| 研究领域[WOS] | Neurosciences & Neurology |
| 关键词[WOS] | OLD-WORLD MONKEY ; DEFAULT-MODE ; FUNCTIONAL CONNECTIVITY ; PHYSIOLOGICAL CONDITION ; STIMULATION ; FMRI ; ACTIVATION ; INFORMATION ; CORTEX ; STATE |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000267674100005 |
| 源URL | [http://ir.ia.ac.cn/handle/173211/3909]  |
| 专题 | 自动化研究所_中国科学院分子影像重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Automat, Key Lab Complex Syst & Intelligence Sci, Med Image Proc Grp, Beijing 100190, Peoples R China 2.Xidian Univ, Life Sci Res Ctr, Sch Life Sci & Technol, Xian 710071, Peoples R China 3.Univ Florida, Dept Psychiat, McKnight Brain Inst, Gainesville, FL 32610 USA 4.Univ Florida, Dept Neurosci, McKnight Brain Inst, Gainesville, FL 32610 USA 5.E China Normal Univ, Dept Psychol, Sch Educ Sci, Shanghai, Peoples R China 6.Capital Med Univ, Beijing Tradit Chinese Med Hosp, Beijing, Peoples R China 7.Capital Univ Med Sci, Dept Radiol, Beijing Tiantan Hosp, Beijing, Peoples R China 8.Xidian Univ, Life Sci Res Ctr, Sch Elect Engn, Xian 710071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Bai, Lijun,Qin, Wei,Tian, Jie,et al. Acupuncture modulates spontaneous activities in the anticorrelated resting brain networks[J]. BRAIN RESEARCH,2009,1279:37-49. |
| APA | Bai, Lijun.,Qin, Wei.,Tian, Jie.,Dong, Minghao.,Pan, Xiaohong.,...&Liu, Yijun.(2009).Acupuncture modulates spontaneous activities in the anticorrelated resting brain networks.BRAIN RESEARCH,1279,37-49. |
| MLA | Bai, Lijun,et al."Acupuncture modulates spontaneous activities in the anticorrelated resting brain networks".BRAIN RESEARCH 1279(2009):37-49. |
入库方式： OAI收割
来源：自动化研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。