Combining spatial and temporal information to explore resting-state networks changes in abstinent heroin-dependent individuals
文献类型：期刊论文
| 作者 | Yuan, Kai2; Qin, Wei2; Dong, Minghao2; Liu, Jixin2; Liu, Peng2; Zhang, Yi2; Sun, Jinbo2; Wang, Wei3; Wang, Yarong3; Li, Qiang3
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| 刊名 | NEUROSCIENCE LETTERS
 |
| 出版日期 | 2010-05-07 |
| 卷号 | 475期号:1页码:20-24 |
| 关键词 | Resting-state Discrete cosine transform (DCT) Heroin Functional connectivity Region of interest (ROI) |
| 英文摘要 | Majority of previous heroin fMRI studies focused on abnormal brain function in heroin-dependent individuals. However, few fMRI studies focused on the resting-state abnormalities in heroin-dependent individuals and assessed the relationship between the resting-state functional connectivity changes and duration of heroin use. In the present study, discrete cosine transform (DCT) was employed to explore spatial distribution of low frequency BOLD oscillations in heroin-dependent individuals and healthy subjects during resting-state; meanwhile resting-state functional connectivity analysis was used to investigate the temporal signatures of overlapping brain regions obtained in DCT analysis among these two groups. Main finding of the present study is that the default mode network (DMN) and rostral anterior cingulate cortex (rACC) network of heroin-dependent individuals were changed compared with healthy subjects. More importantly, these changes negatively correlated with duration of heroin use. These resting-state functional abnormalites in heroin-dependent individuals provided evidence for abnormal functional organization in heroin-dependent individuals, such as functional impairments in decision-making and inhibitory control. (C) 2010 Elsevier Ireland Ltd. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Neurosciences |
| 研究领域[WOS] | Neurosciences & Neurology |
| 关键词[WOS] | DEFAULT-MODE NETWORK ; DRUG-RELATED CUES ; FUNCTIONAL CONNECTIVITY ; ALZHEIMERS-DISEASE ; OPIATE DEPENDENCE ; HUMAN BRAIN ; FMRI ; COCAINE ; STRESS ; SENSITIVITY |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000277966100005 |
| 源URL | [http://ir.ia.ac.cn/handle/173211/3920]  |
| 专题 | 自动化研究所_中国科学院分子影像重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China 2.Xidian Univ, Life Sci Res Ctr, Sch Life Sci & Technol, Xian 710071, Peoples R China 3.Fourth Mil Med Univ, Xian 710038, Shaanxi, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yuan, Kai,Qin, Wei,Dong, Minghao,et al. Combining spatial and temporal information to explore resting-state networks changes in abstinent heroin-dependent individuals[J]. NEUROSCIENCE LETTERS,2010,475(1):20-24. |
| APA | Yuan, Kai.,Qin, Wei.,Dong, Minghao.,Liu, Jixin.,Liu, Peng.,...&Tian, Jie.(2010).Combining spatial and temporal information to explore resting-state networks changes in abstinent heroin-dependent individuals.NEUROSCIENCE LETTERS,475(1),20-24. |
| MLA | Yuan, Kai,et al."Combining spatial and temporal information to explore resting-state networks changes in abstinent heroin-dependent individuals".NEUROSCIENCE LETTERS 475.1(2010):20-24. |
入库方式： OAI收割
来源：自动化研究所
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