Comparison of permissible source region and multispectral data using efficient bioluminescence tomography method
文献类型：期刊论文
| 作者 | Qin, Chenghu1; Zhu, Shouping2; Feng, Jinchao3; Zhong, Jianghong1; Ma, Xibo1 ; Wu, Ping1; Tian, Jie1,2
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| 刊名 | JOURNAL OF BIOPHOTONICS
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| 出版日期 | 2011-11-01 |
| 卷号 | 4期号:11-12页码:824-839 |
| 关键词 | Optical molecular imaging bioluminescence tomography permissible source region spectrally resolved measurements iterative shrinkage thresholding method |
| 英文摘要 | As a novel molecular imaging technology, bioluminescence tomography (BLT) has become an important tool for biomedical research in recent years, which can perform a quantitative reconstruction of an internal light source distribution with the scattered and transmitted bioluminescent signals measured on the external surface of a small animal. However, BLT is severely ill-posed because of complex photon propagation in the biological tissue and limited boundary measured data with noise. Therefore, sufficient a priori knowledge should be fused for the uniqueness and stability of BLT solution. Permissible source region strategy and spectrally resolved measurements are two kinds of a priori knowledge commonly used in BLT reconstruction. This paper compares their performance with simulation and in vivo heterogeneous mouse experiments. In order to improve the efficiency of large-scale source restoration, this paper introduces an efficient iterative shrinkage thresholding method that not only has faster convergence rate but also has better reconstruction accuracy than the modified Newton-type optimization approach. Finally, a discussion of these two kinds of a priori knowledge is given based on the comparison results. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Biochemical Research Methods ; Biophysics |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Biophysics |
| 关键词[WOS] | SPHERICAL-HARMONICS EQUATIONS ; BIOLOGICAL TISSUE ; OPTICAL TOMOGRAPHY ; BOUNDARY-CONDITIONS ; PHOTON TRANSPORT ; LIGHT TRANSPORT ; MOUSE MODELS ; RECONSTRUCTION ; SIMULATION ; ALGORITHM |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000297740500005 |
| 源URL | [http://ir.ia.ac.cn/handle/173211/3921]  |
| 专题 | 自动化研究所_中国科学院分子影像重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Intelligent Med Res Ctr, Inst Automat, Beijing 100190, Peoples R China 2.Xidian Univ, Life Sci Res Ctr, Sch Life Sci & Technol, Xian 710071, Shaanxi, Peoples R China 3.Beijing Univ Technol, Coll Elect Informat & Control Engn, Beijing 100124, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qin, Chenghu,Zhu, Shouping,Feng, Jinchao,et al. Comparison of permissible source region and multispectral data using efficient bioluminescence tomography method[J]. JOURNAL OF BIOPHOTONICS,2011,4(11-12):824-839. |
| APA | Qin, Chenghu.,Zhu, Shouping.,Feng, Jinchao.,Zhong, Jianghong.,Ma, Xibo.,...&Tian, Jie.(2011).Comparison of permissible source region and multispectral data using efficient bioluminescence tomography method.JOURNAL OF BIOPHOTONICS,4(11-12),824-839. |
| MLA | Qin, Chenghu,et al."Comparison of permissible source region and multispectral data using efficient bioluminescence tomography method".JOURNAL OF BIOPHOTONICS 4.11-12(2011):824-839. |
入库方式： OAI收割
来源：自动化研究所
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