Three-dimensional Bioluminescence Tomography based on Bayesian Approach
文献类型：期刊论文
| 作者 | Feng, Jinchao1; Jia, Kebin1; Qin, Chenghu2; Yan, Guorui2; Zhu, Shouping2; Zhang, Xing2; Liu, Junting3; Tian, Jie2,3
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| 刊名 | OPTICS EXPRESS
 |
| 出版日期 | 2009-09-14 |
| 卷号 | 17期号:19页码:16834-16848 |
| 英文摘要 | Bioluminescence tomography (BLT) poses a typical ill-posed inverse problem with a large number of unknowns and a relatively limited number of boundary measurements. It is indispensable to incorporate a priori information into the inverse problem formulation in order to obtain viable solutions. In the paper, Bayesian approach has been firstly suggested to incorporate multiple types of a priori information for BLT reconstruction. Meanwhile, a generalized adaptive Gaussian Markov random field (GAGMRF) prior model for unknown source density estimation is developed to further reduce the ill-posedness of BLT on the basis of finite element analysis. Then the distribution of bioluminescent source can be acquired by maximizing the log posterior probability with respect to a noise parameter and the unknown source density. Furthermore, the use of finite element method makes the algorithm appropriate for complex heterogeneous phantom. The algorithm was validated by numerical simulation of a 3-D micro-CT mouse atlas and physical phantom experiment. The reconstructed results suggest that we are able to achieve high computational efficiency and accurate localization of bioluminescent source. (C) 2009 Optical Society of America |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 类目[WOS] | Optics |
| 研究领域[WOS] | Optics |
| 关键词[WOS] | OPTICAL DIFFUSION TOMOGRAPHY ; IMAGE-RECONSTRUCTION ; PHOTON TRANSPORT ; LIGHT ; SIMULATION ; OPTIMIZATION ; EQUATION ; SYSTEM ; TISSUE ; MOUSE |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000269736100052 |
| 源URL | [http://ir.ia.ac.cn/handle/173211/3987]  |
| 专题 | 自动化研究所_中国科学院分子影像重点实验室 |
| 作者单位 | 1.Beijing Univ Technol, Coll Elect Informat & Control Engn, Beijing 100226, Peoples R China 2.Chinese Acad Sci, Inst Automat, Med Image Proc Grp, Beijing 100190, Peoples R China 3.Xidian Univ, Life Sci Res Ctr, Xian 710071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Feng, Jinchao,Jia, Kebin,Qin, Chenghu,et al. Three-dimensional Bioluminescence Tomography based on Bayesian Approach[J]. OPTICS EXPRESS,2009,17(19):16834-16848. |
| APA | Feng, Jinchao.,Jia, Kebin.,Qin, Chenghu.,Yan, Guorui.,Zhu, Shouping.,...&Tian, Jie.(2009).Three-dimensional Bioluminescence Tomography based on Bayesian Approach.OPTICS EXPRESS,17(19),16834-16848. |
| MLA | Feng, Jinchao,et al."Three-dimensional Bioluminescence Tomography based on Bayesian Approach".OPTICS EXPRESS 17.19(2009):16834-16848. |
入库方式： OAI收割
来源：自动化研究所
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