Amplitude of Low Frequency Fluctuation Abnormalities in Adolescents with Online Gaming Addiction
文献类型：期刊论文
| 作者 | Yuan, Kai1; Jin, Chenwang2; Cheng, Ping1; Yang, Xuejuan1; Dong, Tao1; Bi, Yanzhi1; Xing, Lihong1; von Deneen, Karen M.1; Yu, Dahua1,3; Liu, Junyu4 |
| 刊名 | PLOS ONE
 |
| 出版日期 | 2013-11-04 |
| 卷号 | 8期号:11页码:- |
| 英文摘要 | The majority of previous neuroimaging studies have demonstrated both structural and task-related functional abnormalities in adolescents with online gaming addiction (OGA). However, few functional magnetic resonance imaging (fMRI) studies focused on the regional intensity of spontaneous fluctuations in blood oxygen level-dependent (BOLD) during the resting state and fewer studies investigated the relationship between the abnormal resting-state properties and the impaired cognitive control ability. In the present study, we employed the amplitude of low frequency fluctuation (ALFF) method to explore the local features of spontaneous brain activity in adolescents with OGA and healthy controls during resting-state. Eighteen adolescents with OGA and 18 age-, education-and gender-matched healthy volunteers participated in this study. Compared with healthy controls, adolescents with OGA showed a significant increase in ALFF values in the left medial orbitofrontal cortex (OFC), the left precuneus, the left supplementary motor area (SMA), the right parahippocampal gyrus (PHG) and the bilateral middle cingulate cortex (MCC). The abnormalities of these regions were also detected in previous addiction studies. More importantly, we found that ALFF values of the left medial OFC and left precuneus were positively correlated with the duration of OGA in adolescents with OGA. The ALFF values of the left medial OFC were also correlated with the color-word Stroop test performance. Our results suggested that the abnormal spontaneous neuronal activity of these regions may be implicated in the underlying pathophysiology of OGA. |
| WOS标题词 | Science & Technology |
| 类目[WOS] | Multidisciplinary Sciences |
| 研究领域[WOS] | Science & Technology - Other Topics |
| 关键词[WOS] | INTERNET ADDICTION ; REGIONAL HOMOGENEITY ; STROOP TASK ; BRAIN ; CORTEX ; AREAS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000326503400085 |
| 源URL | [http://ir.ia.ac.cn/handle/173211/4000]  |
| 专题 | 自动化研究所_中国科学院分子影像重点实验室 |
| 作者单位 | 1.Xidian Univ, Sch Life Sci & Technol, Xian, Peoples R China 2.Xi An Jiao Tong Univ, Coll Med, Affiliated Hosp 1, Dept Med Imaging, Xian 710049, Shaanxi, Peoples R China 3.Inner Mongolia Univ Sci & Technol, Sch Informat Engn, Informat Proc Lab, Baotou, Inner Mongolia, Peoples R China 4.Baotou Heping Middle Sch, Baotou, Inner Mongolia, Peoples R China 5.Chinese Acad Sci, Inst Automat, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yuan, Kai,Jin, Chenwang,Cheng, Ping,et al. Amplitude of Low Frequency Fluctuation Abnormalities in Adolescents with Online Gaming Addiction[J]. PLOS ONE,2013,8(11):-. |
| APA | Yuan, Kai.,Jin, Chenwang.,Cheng, Ping.,Yang, Xuejuan.,Dong, Tao.,...&Tian, Jie.(2013).Amplitude of Low Frequency Fluctuation Abnormalities in Adolescents with Online Gaming Addiction.PLOS ONE,8(11),-. |
| MLA | Yuan, Kai,et al."Amplitude of Low Frequency Fluctuation Abnormalities in Adolescents with Online Gaming Addiction".PLOS ONE 8.11(2013):-. |
入库方式： OAI收割
来源：自动化研究所
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