中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 自动化研究所
  3. 中国科学院自动化研究所
  4. 中国科学院分子影像重点实验室
Translational Research of Optical Molecular Imaging for Personalized Medicine

文献类型：期刊论文

作者Qin, C.1,2; Ma, X.1; Tian, J.1,3; Tian, Jie
刊名CURRENT MOLECULAR MEDICINE
出版日期2013-12-01
卷号13期号:10页码:1579-1590
关键词Drug development molecular imaging multi-modality fusion optical imaging personalized medicine translational research
英文摘要In the medical imaging field, molecular imaging is a rapidly developing discipline and forms many imaging modalities, providing us effective tools to visualize, characterize, and measure molecular and cellular mechanisms in complex biological processes of living organisms, which can deepen our understanding of biology and accelerate preclinical research including cancer study and medicine discovery. Among many molecular imaging modalities, although the penetration depth of optical imaging and the approved optical probes used for clinics are limited, it has evolved considerably and has seen spectacular advances in basic biomedical research and new drug development. With the completion of human genome sequencing and the emergence of personalized medicine, the specific drug should be matched to not only the right disease but also to the right person, and optical molecular imaging should serve as a strong adjunct to develop personalized medicine by finding the optimal drug based on an individual's proteome and genome. In this process, the computational methodology and imaging system as well as the biomedical application regarding optical molecular imaging will play a crucial role. This review will focus on recent typical translational studies of optical molecular imaging for personalized medicine followed by a concise introduction. Finally, the current challenges and the future development of optical molecular imaging are given according to the understanding of the authors, and the review is then concluded.
WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Medicine, Research & Experimental
研究领域[WOS]Research & Experimental Medicine
关键词[WOS]PROTEIN-PROTEIN INTERACTIONS ; SPHERICAL-HARMONICS APPROXIMATION ; CERENKOV LUMINESCENCE TOMOGRAPHY ; REPORTER-GENE-EXPRESSION ; BIOLUMINESCENCE TOMOGRAPHY ; IN-VIVO ; LIVING SUBJECTS ; RENILLA-LUCIFERASE ; BIOLOGICAL TISSUE ; LIGHT TRANSPORT
收录类别SCI
语种英语
WOS记录号WOS:000327448200008
源URL[http://ir.ia.ac.cn/handle/173211/4048]  
专题自动化研究所_中国科学院分子影像重点实验室
通讯作者Tian, Jie
作者单位1.Chinese Acad Sci, Inst Automat, Key Lab Mol Imaging, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Bur Acad Local Cooperat, Beijing 100864, Peoples R China
3.Xidian Univ, Sch Life Sci & Technol, Xian 710071, Shaanxi, Peoples R China
推荐引用方式
GB/T 7714		 Qin, C.,Ma, X.,Tian, J.,et al. Translational Research of Optical Molecular Imaging for Personalized Medicine[J]. CURRENT MOLECULAR MEDICINE,2013,13(10):1579-1590.
APA Qin, C.,Ma, X.,Tian, J.,&Tian, Jie.(2013).Translational Research of Optical Molecular Imaging for Personalized Medicine.CURRENT MOLECULAR MEDICINE,13(10),1579-1590.
MLA Qin, C.,et al."Translational Research of Optical Molecular Imaging for Personalized Medicine".CURRENT MOLECULAR MEDICINE 13.10(2013):1579-1590.

入库方式： OAI收割

来源：自动化研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。