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Bioluminescence Tomography by an Iterative Reweighted l(2)-Norm Optimization

文献类型：期刊论文

作者Wu, Ping1; Hu, Yifang2; Wang, Kun1; Tian, Jie1
刊名IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
出版日期2014
卷号61期号:1页码:189-196
关键词Bioluminescence tomography hybrid imaging optical molecular imaging (OMI) 3-D reconstruction
英文摘要Bioluminescence tomography is a promising tool in preclinical research, enabling noninvasive real-time in vivo imaging as well as quantitative analysis in small animal studies. Due to the difficulty of reconstruction, continuous efforts are still made to find more practical and efficient approaches. In this paper, we present an iterative reweighted l(2)-norm optimization incorporating anatomical structures in order to enhance the performance of bioluminescence tomography. The structure priors have been utilized to generate a heterogeneous mouse model by extracting the internal organs and tissues, which can assist in establishing a more precise photon diffusion model, as well as reflecting a more specific position of the reconstruction results inside the mouse. To evaluate the performance of the iterative reweighted approach, several numerical simulation studies including comparative analyses and multisource cases have been conducted to reconstruct the same datasets. The results suggest that the proposed method is able to ensure the accuracy, robustness, and efficiency of bioluminescence tomography. Finally, an in vivo experiment was performed to further validate its feasibility in a practical application.
WOS标题词Science & Technology ; Technology
类目[WOS]Engineering, Biomedical
研究领域[WOS]Engineering
关键词[WOS]IMAGE-RECONSTRUCTION ; OPTICAL TOMOGRAPHY ; IN-VIVO ; SHEDDING LIGHT ; LIMITED DATA ; ALGORITHM ; CANCER ; MODEL
收录类别SCI
语种英语
WOS记录号WOS:000333263300020
源URL[http://ir.ia.ac.cn/handle/173211/4060]  
专题自动化研究所_中国科学院分子影像重点实验室
作者单位1.Chinese Acad Sci, Inst Automat, Key Lab Mol Imaging & Funct Imaging, Beijing 100190, Peoples R China
2.Beijing Jiaotong Univ, Dept Biomed Engn, Sch Comp & Informat Technol, Beijing 100044, Peoples R China
推荐引用方式
GB/T 7714		 Wu, Ping,Hu, Yifang,Wang, Kun,et al. Bioluminescence Tomography by an Iterative Reweighted l(2)-Norm Optimization[J]. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING,2014,61(1):189-196.
APA Wu, Ping,Hu, Yifang,Wang, Kun,&Tian, Jie.(2014).Bioluminescence Tomography by an Iterative Reweighted l(2)-Norm Optimization.IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING,61(1),189-196.
MLA Wu, Ping,et al."Bioluminescence Tomography by an Iterative Reweighted l(2)-Norm Optimization".IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING 61.1(2014):189-196.

入库方式： OAI收割

来源：自动化研究所

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