Comparisons of hybrid radiosity-diffusion model and diffusion equation for bioluminescence tomography in cavity cancer detection
文献类型：期刊论文
| 作者 | Chen, Xueli1; Yang, Defu1; Qu, Xiaochao1; Hu, Hao2,3; Liang, Jimin1; Gao, Xinbo4; Tian, Jie1,5
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| 刊名 | JOURNAL OF BIOMEDICAL OPTICS
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| 出版日期 | 2012-06-01 |
| 卷号 | 17期号:6页码:- |
| 关键词 | bioluminescence tomography hybrid radiosity-diffusion model diffusion equation complicated geometries cavity cancer detection |
| 英文摘要 | Bioluminescence tomography (BLT) has been successfully applied to the detection and therapeutic evaluation of solid cancers. However, the existing BLT reconstruction algorithms are not accurate enough for cavity cancer detection because of neglecting the void problem. Motivated by the ability of the hybrid radiosity-diffusion model (HRDM) in describing the light propagation in cavity organs, an HRDM-based BLT reconstruction algorithm was provided for the specific problem of cavity cancer detection. HRDM has been applied to optical tomography but is limited to simple and regular geometries because of the complexity in coupling the boundary between the scattering and void region. In the provided algorithm, HRDM was first applied to three-dimensional complicated and irregular geometries and then employed as the forward light transport model to describe the bioluminescent light propagation in tissues. Combining HRDM with the sparse reconstruction strategy, the cavity cancer cells labeled with bioluminescent probes can be more accurately reconstructed. Compared with the diffusion equation based reconstruction algorithm, the essentiality and superiority of the HRDM-based algorithm were demonstrated with simulation, phantom and animal studies. An in vivo gastric cancer-bearing nude mouse experiment was conducted, whose results revealed the ability and feasibility of the HRDM-based algorithm in the biomedical application of gastric cancer detection. (C) 2012 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.JBO.17.6.066015] |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences |
| 类目[WOS] | Biochemical Research Methods ; Optics ; Radiology, Nuclear Medicine & Medical Imaging |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Optics ; Radiology, Nuclear Medicine & Medical Imaging |
| 关键词[WOS] | RADIATIVE-TRANSFER EQUATION ; LIGHT-PROPAGATION ; NONSCATTERING REGIONS ; APPROXIMATION MODEL ; PHOTON MIGRATION ; GASTRIC-CANCER ; LOW-SCATTERING ; MOUSE ; RECONSTRUCTION ; SIMULATION |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000305582500048 |
| 源URL | [http://ir.ia.ac.cn/handle/173211/4076]  |
| 专题 | 自动化研究所_中国科学院分子影像重点实验室 |
| 作者单位 | 1.Xidian Univ, Sch Life Sci & Technol, Xian 710126, Shaanxi, Peoples R China 2.Fourth Mil Med Univ, Xijing Hosp, State Key Lab Canc Biol, Xian 710032, Peoples R China 3.Inst Digest Dis, Xian 710032, Peoples R China 4.Xidian Univ, Sch Elect Engn, Video & Image Proc Syst Lab, Xian 710071, Peoples R China 5.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Xueli,Yang, Defu,Qu, Xiaochao,et al. Comparisons of hybrid radiosity-diffusion model and diffusion equation for bioluminescence tomography in cavity cancer detection[J]. JOURNAL OF BIOMEDICAL OPTICS,2012,17(6):-. |
| APA | Chen, Xueli.,Yang, Defu.,Qu, Xiaochao.,Hu, Hao.,Liang, Jimin.,...&Tian, Jie.(2012).Comparisons of hybrid radiosity-diffusion model and diffusion equation for bioluminescence tomography in cavity cancer detection.JOURNAL OF BIOMEDICAL OPTICS,17(6),-. |
| MLA | Chen, Xueli,et al."Comparisons of hybrid radiosity-diffusion model and diffusion equation for bioluminescence tomography in cavity cancer detection".JOURNAL OF BIOMEDICAL OPTICS 17.6(2012):-. |
入库方式： OAI收割
来源：自动化研究所
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