Mapping of bioluminescent images onto CT volume surface for dual-modality BLT and CT imaging
文献类型：期刊论文
| 作者 | Chen, Xueli1,2; Liang, Jimin1; Qu, Xiaochao1; Hou, Yanbin1; Zhu, Shouping1; Chen, Duofang1; Gao, Xinbo2; Tian, Jie1,3
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| 刊名 | JOURNAL OF X-RAY SCIENCE AND TECHNOLOGY
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| 出版日期 | 2012 |
| 卷号 | 20期号:1页码:31-44 |
| 关键词 | Dual-modality imaging bioluminescence tomography (BLT) computed tomography (CT) spatial registration light flux recovering |
| 英文摘要 | We present a method for mapping the two-dimensional (2D) bioluminescent images (BLIs) onto a three-dimensional (3D) body surface derived from the computed tomography (CT) volume data. This mapping includes two closely-related steps, the spatial registration of the 2D BLIs into the coordinate system of the CT volume data and the light flux recovering on the body surface from BLIs. By labeling markers on the body surface, we proposed an effective registration method to achieve the spatial position alignment. The subsequent light flux recovering is presented based on the inverse process of the free-space light transport model and taking the influence of the camera lens diaphragm into account. Incorporating the mapping procedure into the bioluminescence tomography (BLT) reconstruction, we developed a dual-modality BLT and CT imaging framework to provide both optical and anatomical information. The accuracy of the registration and the light flux recovering methods were evaluated via physical phantom experiments. The registration method was found to have a mean error of 0.41 mm and 0.35 mm in horizontal and vertical direction, and the accuracy of the light flux recovering method was below 5%. Furthermore, we evaluated the performance of the dual-modality BLT/CT imaging framework using a mouse phantom. Preliminary results revealed the potential and feasibility of the dual-modality imaging framework. |
| WOS标题词 | Science & Technology ; Technology ; Physical Sciences |
| 类目[WOS] | Instruments & Instrumentation ; Optics ; Physics, Applied |
| 研究领域[WOS] | Instruments & Instrumentation ; Optics ; Physics |
| 关键词[WOS] | TOMOGRAPHY ; RECONSTRUCTION ; MOUSE ; SIMULATION |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000301363700004 |
| 源URL | [http://ir.ia.ac.cn/handle/173211/4081]  |
| 专题 | 自动化研究所_中国科学院分子影像重点实验室 |
| 作者单位 | 1.Xidian Univ, Sch Life Sci & Technol, Xian 710126, Shaanxi, Peoples R China 2.Xidian Univ, Sch Elect Engn, Xian 710126, Shaanxi, Peoples R China 3.Chinese Acad Sci, Inst Automat, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Xueli,Liang, Jimin,Qu, Xiaochao,et al. Mapping of bioluminescent images onto CT volume surface for dual-modality BLT and CT imaging[J]. JOURNAL OF X-RAY SCIENCE AND TECHNOLOGY,2012,20(1):31-44. |
| APA | Chen, Xueli.,Liang, Jimin.,Qu, Xiaochao.,Hou, Yanbin.,Zhu, Shouping.,...&Tian, Jie.(2012).Mapping of bioluminescent images onto CT volume surface for dual-modality BLT and CT imaging.JOURNAL OF X-RAY SCIENCE AND TECHNOLOGY,20(1),31-44. |
| MLA | Chen, Xueli,et al."Mapping of bioluminescent images onto CT volume surface for dual-modality BLT and CT imaging".JOURNAL OF X-RAY SCIENCE AND TECHNOLOGY 20.1(2012):31-44. |
入库方式： OAI收割
来源：自动化研究所
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