Recent advances in bioluminescence tomography: methodology and system as well as application
文献类型：期刊论文
| 作者 | Qin, Chenghu1,4; Feng, Jinchao2; Zhu, Shouping3; Ma, Xibo1 ; Zhong, Jianghong1; Wu, Ping1; Jin, Zhengyu5,6; Tian, Jie1,3
|
| 刊名 | LASER & PHOTONICS REVIEWS
 |
| 出版日期 | 2014 |
| 卷号 | 8期号:1页码:94-114 |
| 关键词 | Bioluminescence tomography biophotonics optical molecular imaging inverse source reconstruction optical imaging instrument multimodality fusion |
| 英文摘要 | Optical molecular imaging has been rapidly developed to noninvasively visualize in vivo physiological and pathological processes involved in normal and suffering organisms at the cellular and molecular levels, in which advanced optical imaging technology and modern molecular biology are being combined to provide a state-of-the-art tool for preclinical biomedical research. Among optical molecular imaging modalities, bioluminescence tomography (BLT) has experienced considerable growth and attracted much attention in recent years for its excellent performance, unique advantages, and high cost-effectiveness. This article focuses on the genesis and development of BLT, especially for its computational methodology, imaging system, and biomedical application. An overview of the advantages and challenges of the conventional planar bioluminescence imaging technique is first described in comparison with currently available molecular imaging modalities. The imaging algorithms for inverse source reconstruction are classified and summarized according to different a priori knowledge, followed by a simple depiction of the uniqueness theorems of BLT solution. Diverse imaging systems for obtaining three-dimensional quantitative information of internal bioluminescent sources are then reviewed. The latest application examples of BLT in tumor study and drug discovery are introduced and compared with other mature imaging technologies. Finally, the paper is concluded and an attractive prospect for BLT ispredicted. |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 类目[WOS] | Optics ; Physics, Applied ; Physics, Condensed Matter |
| 研究领域[WOS] | Optics ; Physics |
| 关键词[WOS] | DIFFUSE OPTICAL TOMOGRAPHY ; RADIATIVE-TRANSFER EQUATION ; FLUORESCENCE MOLECULAR TOMOGRAPHY ; CERENKOV LUMINESCENCE TOMOGRAPHY ; PROTEIN-PROTEIN INTERACTIONS ; TOTAL-VARIATION MINIMIZATION ; PERMISSIBLE SOURCE REGION ; SPHERICAL-HARMONICS APPROXIMATION ; TOTAL VARIATION REGULARIZATION ; MONTE-CARLO-SIMULATION |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000330596500008 |
| 源URL | [http://ir.ia.ac.cn/handle/173211/4082]  |
| 专题 | 自动化研究所_中国科学院分子影像重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Automat, Intelligent Med Res Ctr, Beijing 100190, Peoples R China 2.Beijing Univ Technol, Coll Elect Informat & Control Engn, Beijing 100124, Peoples R China 3.Xidian Univ, Sch Life Sci & Technol, Life Sci Res Ctr, Xian 710071, Shaanxi, Peoples R China 4.Chinese Acad Sci, Bur Acad Local Cooperat, Beijing 100864, Peoples R China 5.Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Radiol, Beijing 100730, Peoples R China 6.Peking Union Med Coll, Beijing 100730, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qin, Chenghu,Feng, Jinchao,Zhu, Shouping,et al. Recent advances in bioluminescence tomography: methodology and system as well as application[J]. LASER & PHOTONICS REVIEWS,2014,8(1):94-114. |
| APA | Qin, Chenghu.,Feng, Jinchao.,Zhu, Shouping.,Ma, Xibo.,Zhong, Jianghong.,...&Tian, Jie.(2014).Recent advances in bioluminescence tomography: methodology and system as well as application.LASER & PHOTONICS REVIEWS,8(1),94-114. |
| MLA | Qin, Chenghu,et al."Recent advances in bioluminescence tomography: methodology and system as well as application".LASER & PHOTONICS REVIEWS 8.1(2014):94-114. |
入库方式： OAI收割
来源：自动化研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。