Regional homogeneity abnormalities in patients with interictal migraine without aura: a resting-state study
文献类型：期刊论文
| 作者 | Yu, Dahua1,2; Yuan, Kai1; Zhao, Ling3; Zhao, Limei1; Dong, Minghao1; Liu, Peng1; Wang, Guihong1,4; Liu, Jixin1; Sun, Jinbo1; Zhou, Guangyu1 |
| 刊名 | NMR IN BIOMEDICINE
 |
| 出版日期 | 2012-05-01 |
| 卷号 | 25期号:5页码:806-812 |
| 关键词 | migraine without aura regional homogeneity (ReHo) resting state functional MRI (fMRI) supplementary motor area (SMA) prefrontal cortex (PFC) rostral anterior cingulate cortex (rACC) orbitofrontal cortex (OFC) |
| 英文摘要 | Previous studies have provided evidence of structural and task-related functional changes in the brains of patients with migraine without aura. Resting-state brain activity in patients with migraine provides clues to the pathophysiology of the disease. However, few studies have focused on the resting-state abnormalities in patients with migraine without aura. In the current study, we employed a data-driven method, regional homogeneity (ReHo), to analyze the local features of spontaneous brain activity in patients with migraine without aura during the resting state. Twenty-six patients with migraine without aura and 26 age-, education- and gender-matched healthy volunteers participated in this study. Compared with healthy controls, patients with migraine without aura showed a significant decrease in ReHo values in the right rostral anterior cingulate cortex (rACC), the prefrontal cortex (PFC), the orbitofrontal cortex (OFC) and the supplementary motor area (SMA). In addition, we found that ReHo values were negatively correlated with the duration of disease in the right rACC and PFC. Our results suggest that the resting-state abnormalities of these regions may be associated with functional impairments in pain processing in patients with migraine without aura. We hope that our results will improve the understanding of migraine. Copyright (C) 2011 John Wiley & Sons, Ltd. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Technology |
| 类目[WOS] | Biophysics ; Radiology, Nuclear Medicine & Medical Imaging ; Spectroscopy |
| 研究领域[WOS] | Biophysics ; Radiology, Nuclear Medicine & Medical Imaging ; Spectroscopy |
| 关键词[WOS] | HEROIN-DEPENDENT INDIVIDUALS ; MEDIAL FRONTAL-CORTEX ; HUMAN ORBITOFRONTAL CORTEX ; VOXEL-BASED MORPHOMETRY ; GREY-MATTER CHANGES ; HUMAN BRAIN ; PAIN PERCEPTION ; GRAY-MATTER ; FUNCTIONAL CONNECTIVITY ; NEURAL ACTIVITY |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000302617600012 |
| 源URL | [http://ir.ia.ac.cn/handle/173211/4101]  |
| 专题 | 自动化研究所_中国科学院分子影像重点实验室 |
| 作者单位 | 1.Xidian Univ, Life Sci Res Ctr, Sch Life Sci & Technol, Xian 710071, Shaanxi, Peoples R China 2.Inner Mongolia Univ Sci & Technol, Informat Proc Lab, Sch Informat Engn, Baotou, Inner Mongolia, Peoples R China 3.Chengdu Univ Tradit Chinese Med, Teaching Hosp 3, Chengdu, Sichuan, Peoples R China 4.Xidian Univ, Dept Appl Math, Sch Life Sci & Technol, Xian 710071, Shaanxi, Peoples R China 5.Chinese Acad Sci, Inst Automat, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yu, Dahua,Yuan, Kai,Zhao, Ling,et al. Regional homogeneity abnormalities in patients with interictal migraine without aura: a resting-state study[J]. NMR IN BIOMEDICINE,2012,25(5):806-812. |
| APA | Yu, Dahua.,Yuan, Kai.,Zhao, Ling.,Zhao, Limei.,Dong, Minghao.,...&Tian, Jie.(2012).Regional homogeneity abnormalities in patients with interictal migraine without aura: a resting-state study.NMR IN BIOMEDICINE,25(5),806-812. |
| MLA | Yu, Dahua,et al."Regional homogeneity abnormalities in patients with interictal migraine without aura: a resting-state study".NMR IN BIOMEDICINE 25.5(2012):806-812. |
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