Intraoperative Imaging-Guided Cancer Surgery: From Current Fluorescence Molecular Imaging Methods to Future Multi-Modality Imaging Technology
文献类型：期刊论文
| 作者 | Chi, Chongwei1 ; Du, Yang1; Ye, Jinzuo1; Kou, Deqiang3; Qiu, Jingdan3; Wang, Jiandong3; Tian, Jie1; Chen, Xiaoyuan2
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| 刊名 | THERANOSTICS
 |
| 出版日期 | 2014 |
| 卷号 | 4期号:11页码:1072-1084 |
| 关键词 | Optical molecular imaging Intraoperative imaging-guided cancer surgery Near-infrared fluorescence Multi-modality Imaging Indocyanine green |
| 英文摘要 | Cancer is a major threat to human health. Diagnosis and treatment using precision medicine is expected to be an effective method for preventing the initiation and progression of cancer. Although anatomical and functional imaging techniques such as radiography, computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography (PET) have played an important role for accurate preoperative diagnostics, for the most part these techniques cannot be applied intraoperatively. Optical molecular imaging is a promising technique that provides a high degree of sensitivity and specificity in tumor margin detection. Furthermore, existing clinical applications have proven that optical molecular imaging is a powerful intraoperative tool for guiding surgeons performing precision procedures, thus enabling radical resection and improved survival rates. However, detection depth limitation exists in optical molecular imaging methods and further breakthroughs from optical to multi-modality intraoperative imaging methods are needed to develop more extensive and comprehensive intraoperative applications. Here, we review the current intraoperative optical molecular imaging technologies, focusing on contrast agents and surgical navigation systems, and then discuss the future prospects of multi-modality imaging technology for intraoperative imaging-guided cancer surgery. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Medicine, Research & Experimental |
| 研究领域[WOS] | Research & Experimental Medicine |
| 关键词[WOS] | SENTINEL LYMPH-NODE ; NEAR-INFRARED FLUORESCENCE ; INDOCYANINE GREEN FLUORESCENCE ; EARLY GASTRIC-CANCER ; CELL-PENETRATING PEPTIDES ; HUMAN SERUM-ALBUMIN ; IMMOBILIZED DIAGNOSTIC KIT ; FLAP BREAST RECONSTRUCTION ; CYSTEINE PROTEASE ACTIVITY ; ACTIVITY-BASED PROBES |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000345212900002 |
| 源URL | [http://ir.ia.ac.cn/handle/173211/4112]  |
| 专题 | 自动化研究所_中国科学院分子影像重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Automat, Key Lab Mol Imaging Chinese Acad Sci, Beijing 100190, Peoples R China 2.NIBIB, NIH, Lab Mol Imaging & Nanomed, Bethesda, MD 20814 USA 3.Gen Hosp Peoples Liberat Army, Dept Gen Surg, Beijing 100853, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chi, Chongwei,Du, Yang,Ye, Jinzuo,et al. Intraoperative Imaging-Guided Cancer Surgery: From Current Fluorescence Molecular Imaging Methods to Future Multi-Modality Imaging Technology[J]. THERANOSTICS,2014,4(11):1072-1084. |
| APA | Chi, Chongwei.,Du, Yang.,Ye, Jinzuo.,Kou, Deqiang.,Qiu, Jingdan.,...&Chen, Xiaoyuan.(2014).Intraoperative Imaging-Guided Cancer Surgery: From Current Fluorescence Molecular Imaging Methods to Future Multi-Modality Imaging Technology.THERANOSTICS,4(11),1072-1084. |
| MLA | Chi, Chongwei,et al."Intraoperative Imaging-Guided Cancer Surgery: From Current Fluorescence Molecular Imaging Methods to Future Multi-Modality Imaging Technology".THERANOSTICS 4.11(2014):1072-1084. |
入库方式： OAI收割
来源：自动化研究所
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