Unraveling the genome structure of cyanobacterial podovirus A-4L with long direct terminal repeats
文献类型：期刊论文
| 作者 | Ou, Tong; Liao, Xiang-Yong; Gao, Xiao-Chan; Xu, Xu-Dong; Zhang, Qi-Ya |
| 刊名 | VIRUS RESEARCH
 |
| 出版日期 | 2015-05-04 |
| 卷号 | 203页码:4-9 |
| ISSN号 | 0168-1702 |
| 关键词 | Cyanobacterial podovirus A-4L Cyanophage Genomic analysis Terminal repeat Cyanobacterial virus-host model system |
| 通讯作者 | Zhang, QY (reprint author), Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Peoples R China. |
| 英文摘要 | The freshwater cyanobacterial virus (cyanophage) A-4L, a podovirus, can infect the model cyanobacterium Anabaena sp. strain PCC 7120 resulting in a high burst size and forming concentric plaques on its lawns. The complete genome sequence of A-4L was determined by the combination of high-throughput sequencing, terminal transferase-mediated polymerase chain reaction and restriction mapping. It contains 41,750 bp with 810 bp direct terminal repeats and 38 potential open reading frames. As compared with other cyanobacterial podoviruses in diverse ecosystems, the A-4L has the longest terminal repeat and shares similar genome organizations with freshwater members. Furthermore, phylogenetic analysis based on concatenated sequences of eight core proteins indicated that freshwater cyanobacterial podoviruses were clustered together and distinct from marine counterparts, suggesting a clear divergence in the cyanobacterial podovirus lineage between freshwater and marine ecosystems. Our findings uncover the unique genome structure of A-4L which contains long direct terminal repeats, and create the first model system to address knowledge gaps in understanding cyanobacterial virus-host interactions at the molecular level. (C) 2015 Elsevier B.V. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Virology |
| 研究领域[WOS] | Virology |
| 关键词[WOS] | FRESH-WATER ; MICROCYSTIS-AERUGINOSA ; PHORMIDIUM-FOVEOLARUM ; MARINE SYNECHOCOCCUS ; PHOTOSYNTHESIS GENES ; CYANOPHAGE ; SEQUENCE ; PHAGE ; ANABAENA ; STRATEGIES |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000356746200002 |
| 源URL | [http://ir.ihb.ac.cn/handle/342005/23887]  |
| 专题 | 水生生物研究所_鱼类生物学及渔业生物技术研究中心_期刊论文 |
| 作者单位 | Univ Chinese Acad Sci, State Key Lab Freshwater Ecol & Biotechnol, Inst Hydrobiol, Chinese Acad Sci, Wuhan 430072, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ou, Tong,Liao, Xiang-Yong,Gao, Xiao-Chan,et al. Unraveling the genome structure of cyanobacterial podovirus A-4L with long direct terminal repeats[J]. VIRUS RESEARCH,2015,203:4-9. |
| APA | Ou, Tong,Liao, Xiang-Yong,Gao, Xiao-Chan,Xu, Xu-Dong,&Zhang, Qi-Ya.(2015).Unraveling the genome structure of cyanobacterial podovirus A-4L with long direct terminal repeats.VIRUS RESEARCH,203,4-9. |
| MLA | Ou, Tong,et al."Unraveling the genome structure of cyanobacterial podovirus A-4L with long direct terminal repeats".VIRUS RESEARCH 203(2015):4-9. |
入库方式： OAI收割
来源：水生生物研究所
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