Characterizations of four toll-like receptor 4s in grass carp Ctenopharyngodon idellus and their response to grass carp reovirus infection and lipopolysaccharide stimulation
文献类型：期刊论文
| 作者 | Pei, Y. Y.1,2; Huang, R.1; Li, Y. M.1; Liao, L. J.1; Zhu, Z. Y.1; Wang, Y. P.1 |
| 刊名 | JOURNAL OF FISH BIOLOGY
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| 出版日期 | 2015-03-01 |
| 卷号 | 86期号:3页码:1098-1108 |
| 关键词 | gene expression grass carp reovirus subcellular localization tissue distribution virus infection |
| ISSN号 | 0022-1112 |
| 通讯作者 | Wang, YP (reprint author), Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China. |
| 英文摘要 | In this study, the subcellular localization, tissue distribution and response to grass carp reovirus (GCRV) infection and lipopolysaccharide (LPS) stimulation of four grass carp Ctenopharyngodon idellus toll-like receptor 4 (tlr4) genes were investigated. All four genes were constitutively expressed in all tissues studied, but the subcellular localization and tissue exhibiting the highest expression differed for each protein. Following GCRV infection, all the four tlr4s were upregulated in all tissues examined, and stimulation of C. idellus kidney (CIK) cells with LPS resulted in downregulation of all four tlr4s. These results provide a foundation for further investigation of tlr4 genes in bony fishes. (C) 2015 The Fisheries Society of the British Isles |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Fisheries ; Marine & Freshwater Biology |
| 研究领域[WOS] | Fisheries ; Marine & Freshwater Biology |
| 关键词[WOS] | CATFISH ICTALURUS-PUNCTATUS ; RESPIRATORY SYNCYTIAL VIRUS ; GENE FAMILY ; PATHOGEN RECOGNITION ; CHANNEL CATFISH ; INNATE IMMUNITY ; TLR4 GENE ; SIGNAL-TRANSDUCTION ; EXPRESSION ANALYSIS ; PATHWAY |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000351356700013 |
| 源URL | [http://ir.ihb.ac.cn/handle/342005/23901]  |
| 专题 | 水生生物研究所_鱼类生物学及渔业生物技术研究中心_期刊论文 |
| 作者单位 | 1.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Pei, Y. Y.,Huang, R.,Li, Y. M.,et al. Characterizations of four toll-like receptor 4s in grass carp Ctenopharyngodon idellus and their response to grass carp reovirus infection and lipopolysaccharide stimulation[J]. JOURNAL OF FISH BIOLOGY,2015,86(3):1098-1108. |
| APA | Pei, Y. Y.,Huang, R.,Li, Y. M.,Liao, L. J.,Zhu, Z. Y.,&Wang, Y. P..(2015).Characterizations of four toll-like receptor 4s in grass carp Ctenopharyngodon idellus and their response to grass carp reovirus infection and lipopolysaccharide stimulation.JOURNAL OF FISH BIOLOGY,86(3),1098-1108. |
| MLA | Pei, Y. Y.,et al."Characterizations of four toll-like receptor 4s in grass carp Ctenopharyngodon idellus and their response to grass carp reovirus infection and lipopolysaccharide stimulation".JOURNAL OF FISH BIOLOGY 86.3(2015):1098-1108. |
入库方式： OAI收割
来源：水生生物研究所
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