Vitellogenic responses of 17 beta-estradiol and bisphenol A in male Chinese loach (Misgurnus anguillicaudatus)
文献类型：期刊论文
| 作者 | Lv, Xuefei; Zhou, Qunfang; Song, Maoyong; Jiang, Guibin; Shao, Jing |
| 刊名 | ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
 |
| 出版日期 | 2007-09 |
| 卷号 | 24期号:2页码:155-159 |
| 关键词 | bisphenol a chinese loach chemical interaction endocrine disruption estradiol experimental animal Misgurnus anguillicaudatus vitellogenin |
| 英文摘要 | in this study, male Chinese loaches were exposed to 17 beta-estradiol (E-2), bisphenol A (BPA) and their mixtures, respectively, for 42 days using a semi-static exposure system. Plasma vitellogenin (Vtg) in male Chinese loaches was used as the determining endpoint. The results demonstrated that male Chinese loaches were sensitive to E-2, and the vitellogenic responses showed time- and dose-dependent increase. Similarly, BPA induced the estrogenic effects in male Chinese loaches, and the vitellogenic response increased in a time- and dose-dependent manner. The synthesis of Vtg was initiated by the exposure to higher level of BPA (500 mu g/L) within 7 days, and a relative long-term exposure to lower concentrations of BPA (10-100 mu g/L) also led to the production of Vtg. The estrogenic effect of the binary mixture of E2 and BPA also showed a time- and dose-dependent response, which was more potent than that of individual compounds, and Vtg contents in the binary mixture group were higher than the summation of Vtg contents in the single-compound groups at the same concentration. (c) 2007 Elsevier B.V. All rights reserved. |
| WOS记录号 | WOS:000248980700012 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/22517]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Lv, Xuefei,Zhou, Qunfang,Song, Maoyong,et al. Vitellogenic responses of 17 beta-estradiol and bisphenol A in male Chinese loach (Misgurnus anguillicaudatus)[J]. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,2007,24(2):155-159. |
| APA | Lv, Xuefei,Zhou, Qunfang,Song, Maoyong,Jiang, Guibin,&Shao, Jing.(2007).Vitellogenic responses of 17 beta-estradiol and bisphenol A in male Chinese loach (Misgurnus anguillicaudatus).ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,24(2),155-159. |
| MLA | Lv, Xuefei,et al."Vitellogenic responses of 17 beta-estradiol and bisphenol A in male Chinese loach (Misgurnus anguillicaudatus)".ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 24.2(2007):155-159. |
入库方式： OAI收割
来源：生态环境研究中心
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