Immunopotentiator-Loaded Polymeric Microparticles as Robust Adjuvant to Improve Vaccine Efficacy
文献类型：期刊论文
| 作者 | Zhang, Weifeng1,2; Wang, Lianyan1; Yang, Tingyuan1; Liu, Yuan1,2; Chen, Xiaoming1,2; Liu, Qi1,2; Jia, Jilei1,2; Ma, Guanghui1,3 |
| 刊名 | PHARMACEUTICAL RESEARCH
 |
| 出版日期 | 2015-09-01 |
| 卷号 | 32期号:9页码:2837-2850 |
| 关键词 | adjuvant imiquimod immune response microparticles subunit vaccine |
| ISSN号 | 0724-8741 |
| 英文摘要 | Adjuvants are required to ensure the efficacy of subunit vaccines. Incorporating molecular immunopotentiators within particles could overcome drawbacks of molecular adjuvants (such as solubility and toxicity), and improve adjuvanticity of particles, achieving stronger adjuvant activity. Aim of this study is to evaluate the adjuvanticity of immunopotentiator-loaded polymeric particles for subunit vaccine. |
| WOS标题词 | Science & Technology ; Physical Sciences ; Life Sciences & Biomedicine |
| 类目[WOS] | Chemistry, Multidisciplinary ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Chemistry ; Pharmacology & Pharmacy |
| 关键词[WOS] | IMMUNE-RESPONSES ; ACETALATED DEXTRAN ; CELL-ACTIVATION ; ANTIGEN ; NANOPARTICLES ; DELIVERY ; IMIQUIMOD ; CD69 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000359140800004 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/19427]  |
| 专题 | 过程工程研究所_生化工程国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Natl Key Lab Biochem Engn, PLA Key Lab Biopharmaceut Prod & Formulat Engn, Inst Proc Engn, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300072, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Weifeng,Wang, Lianyan,Yang, Tingyuan,et al. Immunopotentiator-Loaded Polymeric Microparticles as Robust Adjuvant to Improve Vaccine Efficacy[J]. PHARMACEUTICAL RESEARCH,2015,32(9):2837-2850. |
| APA | Zhang, Weifeng.,Wang, Lianyan.,Yang, Tingyuan.,Liu, Yuan.,Chen, Xiaoming.,...&Ma, Guanghui.(2015).Immunopotentiator-Loaded Polymeric Microparticles as Robust Adjuvant to Improve Vaccine Efficacy.PHARMACEUTICAL RESEARCH,32(9),2837-2850. |
| MLA | Zhang, Weifeng,et al."Immunopotentiator-Loaded Polymeric Microparticles as Robust Adjuvant to Improve Vaccine Efficacy".PHARMACEUTICAL RESEARCH 32.9(2015):2837-2850. |
入库方式： OAI收割
来源：过程工程研究所
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