Surface functionalized barium sulfate nanoparticles: controlled in situ synthesis and application in bone cement
文献类型：期刊论文
| 作者 | Fang, Chao ; Hou, Ruixia ; Zhou, Kefeng ; Hua, Feibin ; Cong, Yang ; Zhang, Jianfeng ; Fu, Jun ; Cheng, Ya-Jun |
| 刊名 | JOURNAL OF MATERIALS CHEMISTRY B
 |
| 出版日期 | 2014 |
| 卷号 | 2期号:9页码:1264 |
| 中文摘要 | The controlled synthesis of surface functionatized BaSO4 nanoparticles with a diameter below 50 nm is achieved by combining the in situ generation of SO42- and the use of a difunctional surface modification agent, (2-(methacryloyloxy)ethyldimethyl-(3-sulfopropyl)ammoniumhydroxide (MSAH). Particularly, a pre-decomposition process of the SO42- precursor (S2O82-) is applied to decouple the in situ generation of SO42- and precipitation of BaSO4. As a result, the nucleation and growth of the BaSO4 particles is manipulated, which significantly reduces the particle size. Different combinations of the pre-decomposition time and MSAH/BaCl2 molar ratios showed a remarkable influence on the morphology and surface functionality of the BaSO4 particles. Furthermore, the morphology control by using other difunctional surface modification agents e.g. 3-sulfopropylmethacrylate potassium salt (SMPS) and 2-acrylamido-2-methylpropane sulfonic add (AMSA) is examined. The MSAH-functionalized BaSO4 nanoparticles, used as s filler in bone cements, effectively improved the bending modulus and compressive strength of the poly (methyl methacrylate), PMMA, bone cements. The bone cement with MSAH-functionalized BaSO4 nanoparticles exhibited good radiopacity. Moreover, in vitro cell culture experiments demonstrated an improved biocompatibility compared to the bare BaSO4 particles. The MSAH-functionatized BaSO4 nanoparticles may be an ideal candidate material as a bone cement filler. |
| 公开日期 | 2015-09-20 |
| 源URL | [http://ir.nimte.ac.cn/handle/174433/11911]  |
| 专题 | 宁波材料技术与工程研究所_2014专题 |
| 推荐引用方式 GB/T 7714 | Fang, Chao,Hou, Ruixia,Zhou, Kefeng,et al. Surface functionalized barium sulfate nanoparticles: controlled in situ synthesis and application in bone cement[J]. JOURNAL OF MATERIALS CHEMISTRY B,2014,2(9):1264. |
| APA | Fang, Chao.,Hou, Ruixia.,Zhou, Kefeng.,Hua, Feibin.,Cong, Yang.,...&Cheng, Ya-Jun.(2014).Surface functionalized barium sulfate nanoparticles: controlled in situ synthesis and application in bone cement.JOURNAL OF MATERIALS CHEMISTRY B,2(9),1264. |
| MLA | Fang, Chao,et al."Surface functionalized barium sulfate nanoparticles: controlled in situ synthesis and application in bone cement".JOURNAL OF MATERIALS CHEMISTRY B 2.9(2014):1264. |
入库方式： OAI收割
来源：宁波材料技术与工程研究所
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