Intervention-induced enhancement in intrinsic brain activity in healthy older adults
文献类型：期刊论文
| 作者 | Yin, Shufei1,2; Zhu, Xinyi1 ; Li, Rui1,3; Niu, Yanan1; Wang, Baoxi1,2; Zheng, Zhiwei1,2; Huang, Xin1,2; Huo, Lijuan1,2; Li, Juan1,3
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| 刊名 | SCIENTIFIC REPORTS
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| 出版日期 | 2014-12-04 |
| 卷号 | 4期号:0页码:7309 |
| ISSN号 | 2045-2322 |
| 英文摘要 | This study examined the effects of a multimodal intervention on spontaneous brain activity in healthy older adults. Seventeen older adults received a six-week intervention that consisted of cognitive training, Tai Chi exercise, and group counseling, while 17 older adults in a control group attended health knowledge lectures. The intervention group demonstrated enhanced memory and social support compared to the control group. The amplitude of low frequency fluctuations (ALFF) in the middle frontal gyrus, superior frontal gyrus, and anterior cerebellum lobe was enhanced for the intervention group, while the control group showed reduced ALFF in these three regions. Moreover, changes in trail-making performance and well-being could be predicted by the intervention-induced changes in ALFF. Additionally, individual differences in the baseline ALFF were correlated with intervention-related changes in behavioral performance. These findings suggest that a multimodal intervention is effective in improving cognitive functions and well-being and can induce functional changes in the aging brain. The study extended previous training studies by suggesting resting-state ALFF as a marker of intervention-induced plasticity in older adults. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000346267700003 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/13726]  |
| 专题 | 心理研究所_中国科学院心理健康重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Psychol, Ctr Aging Psychol, Key Lab Mental Hlth, Beijing, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Chinese Acad Sci, Inst Psychol, Magnet Resonance Imaging Res Ctr, Beijing 100101, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yin, Shufei,Zhu, Xinyi,Li, Rui,et al. Intervention-induced enhancement in intrinsic brain activity in healthy older adults[J]. SCIENTIFIC REPORTS,2014,4(0):7309. |
| APA | Yin, Shufei.,Zhu, Xinyi.,Li, Rui.,Niu, Yanan.,Wang, Baoxi.,...&Li, Juan.(2014).Intervention-induced enhancement in intrinsic brain activity in healthy older adults.SCIENTIFIC REPORTS,4(0),7309. |
| MLA | Yin, Shufei,et al."Intervention-induced enhancement in intrinsic brain activity in healthy older adults".SCIENTIFIC REPORTS 4.0(2014):7309. |
入库方式： OAI收割
来源：心理研究所
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