中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Neural Correlates of Prospective Memory in Individuals With Schizotypal Personality Features

文献类型:期刊论文

作者Wang, Ya1; Yang, Tian-xiao1; Su, Li2; Yan, Chao1; Wang, Yi1; Huang, Jia1; Fan, Ming-xia3; Yin, Da-zi3; Jin, Zhen4; Zeng, Ya-wei4
刊名NEUROPSYCHOLOGY
出版日期2014-05-01
卷号28期号:3页码:373-381
关键词prospective memory schizotypal personality feature functional imaging
ISSN号0894-4105
英文摘要Objective: Prospective memory (PM) refers to the ability to remember to perform actions in the future. Schizophrenia spectrum disorders show impairments in PM but neural correlates of these impairments remain unclear. The present study aimed to examine brain activation during PM to identify impairments in individuals with schizotypal personality features. Method: Nineteen participants with schizotypal features and 22 healthy controls participated in a functional MRI experiment while performing a PM task. Results: Results showed that the prefrontal cortex (including Brodmann Area [ BA] 10), middle temporal gyrus, and precuneus were activated when performing the PM task compared with baseline. The schizotypal and control groups did not differ in behavioral PM performance. However, participants with schizotypal features showed decreased activations in the inferior and medial frontal lobes (BA 45, and 8). Conclusions: These results confirmed that the PM network involves prefrontal cortex, including BA 10. The lower activation in prefrontal cortex of individuals with schizotypal features when performing a PM task indicates brain activation abnormality. Notably, this abnormality may occur in the absence of any behavioral manifestation. Our findings support the hypothesis of frontal lobe involvement in PM deficits observed in individuals with schizotypal features.
收录类别SSCI
语种英语
WOS记录号WOS:000335334000007
源URL[http://ir.psych.ac.cn/handle/311026/14236]  
专题心理研究所_中国科学院心理健康重点实验室
作者单位1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 100101, Peoples R China
2.Univ Cambridge, Dept Psychol, Cambridge, England
3.E China Normal Univ, Dept Phys, Shanghai 200062, Peoples R China
4.Beijing 306 Hosp, MRI Div, Beijing, Peoples R China
5.Griffith Univ, Behav Basis Hlth Program, Griffith Hlth Inst, Brisbane, Qld 4111, Australia
6.Griffith Univ, Sch Appl Psychol, Brisbane, Qld 4111, Australia
7.Univ Penn, Dept Psychiat, Perelman Sch Med, Philadelphia, PA 19104 USA
8.Philadelphia Vet Adm Med Ctr, Philadelphia, PA USA
9.Chinese Acad Sci, Inst Psychol, Magnet Resonance Imaging Res Ctr, Beijing 100864, Peoples R China
推荐引用方式
GB/T 7714
Wang, Ya,Yang, Tian-xiao,Su, Li,et al. Neural Correlates of Prospective Memory in Individuals With Schizotypal Personality Features[J]. NEUROPSYCHOLOGY,2014,28(3):373-381.
APA Wang, Ya.,Yang, Tian-xiao.,Su, Li.,Yan, Chao.,Wang, Yi.,...&Chan, Raymond C. K..(2014).Neural Correlates of Prospective Memory in Individuals With Schizotypal Personality Features.NEUROPSYCHOLOGY,28(3),373-381.
MLA Wang, Ya,et al."Neural Correlates of Prospective Memory in Individuals With Schizotypal Personality Features".NEUROPSYCHOLOGY 28.3(2014):373-381.

入库方式: OAI收割

来源:心理研究所

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