Improvement of white matter and functional connectivity abnormalities by repetitive transcranial magnetic stimulation in crossed aphasia in dextral
文献类型：期刊论文
| 作者 | Lu, Haitao1; Wu, Haiyan2 ; Cheng, Hewei3; Wei, Dongjie3; Wang, Xiaoyan1; Fan, Yong3; Zhang, Hao1; Zhang, Tong1
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| 刊名 | INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
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| 出版日期 | 2014 |
| 卷号 | 7期号:10页码:3659-3668 |
| 关键词 | Crossed aphasia in dextral diffusion tensor imaging functional magnetic resonance imaging positron emission tomography repetitive transcranial magnetic stimulation |
| ISSN号 | 1940-5901 |
| 英文摘要 | As a special aphasia, the occurrence of crossed aphasia in dextral (CAD) is unusual. This study aims to improve the language ability by applying 1 Hz repetitive transcranial magnetic stimulation (rTMS). We studied multiple modality imaging of structural connectivity (diffusion tensor imaging), functional connectivity (resting fMRI), PET, and neurolinguistic analysis on a patient with CAD. Furthermore, we applied rTMS of 1 Hz for 40 times and observed the language function improvement. The results indicated that a significantly reduced structural and function connectivity was found in DTI and fMRI data compared with the control. The PET imaging showed hypo-metabolism in right hemisphere and left cerebellum. In conclusion, one of the mechanisms of CAD is that right hemisphere is the language dominance. Stimulating left Wernicke area could improve auditory comprehension, stimulating left Broca's area could enhance expression, and the results outlasted 6 months by 1 Hz rTMS balancing the excitability inter-hemisphere in CAD. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000345121100073 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/13448]  |
| 专题 | 心理研究所_中国科学院行为科学重点实验室 |
| 作者单位 | 1.Capital Med Univ, Dept Neurorehabil, Sch Rehabil Med, China Rehabil Res Ctr, Beijing 100068, Peoples R China 2.Chinese Acad Sci, Inst Psychol, Key Lab Behav Sci, Beijing 100101, Peoples R China 3.Chinese Acad Sci, Inst Automat, Ctr Brainnetome, Natl Lab Pattern Recognit, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lu, Haitao,Wu, Haiyan,Cheng, Hewei,et al. Improvement of white matter and functional connectivity abnormalities by repetitive transcranial magnetic stimulation in crossed aphasia in dextral[J]. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE,2014,7(10):3659-3668. |
| APA | Lu, Haitao.,Wu, Haiyan.,Cheng, Hewei.,Wei, Dongjie.,Wang, Xiaoyan.,...&Zhang, Tong.(2014).Improvement of white matter and functional connectivity abnormalities by repetitive transcranial magnetic stimulation in crossed aphasia in dextral.INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE,7(10),3659-3668. |
| MLA | Lu, Haitao,et al."Improvement of white matter and functional connectivity abnormalities by repetitive transcranial magnetic stimulation in crossed aphasia in dextral".INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE 7.10(2014):3659-3668. |
入库方式： OAI收割
来源：心理研究所
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