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Unraveling the Miswired Connectome: A Developmental Perspective
文献类型：期刊论文
| 作者 | Di Martino, Adriana1; Fair, Damien A.2,3,4; Kelly, Clare1; Satterthwaite, Theodore D.5; Castellanos, F. Xavier1,6; Thomason, Moriah E.7,8; Craddock, R. Cameron6,9; Luna, Beatriz10; Leventhal, Bennett L.11; Zuo, Xi-Nian12,13,14
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| 刊名 | NEURON
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| 出版日期 | 2014-09-17 |
| 卷号 | 83期号:6页码:1335-1353 |
| ISSN号 | 0896-6273 |
| 英文摘要 | The vast majority of mental illnesses can be conceptualized as developmental disorders of neural interactions within the connectome, or developmental miswiring. The recent maturation of pediatric in vivo brain imaging is bringing the identification of clinically meaningful brain-based biomarkers of developmental disorders within reach. Even more auspicious is the ability to study the evolving connectome throughout life, beginning in utero, which promises to move the field from topological phenomenology to etiological nosology. Here, we scope advances in pediatric imaging of the brain connectome as the field faces the challenge of unraveling developmental miswiring. We highlight promises while also providing a pragmatic review of the many obstacles ahead that must be overcome to significantly impact public health. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000342502400019 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/14237]  |
| 专题 | 心理研究所_中国科学院行为科学重点实验室 |
| 作者单位 | 1.NYU, Langone Med Ctr, Ctr Child Study, Dept Child & Adolescent Psychiat, New York, NY 10016 USA 2.Oregon Hlth & Sci Univ, Dept Behav Neurosci, Portland, OR 97329 USA 3.Oregon Hlth & Sci Univ, Dept Psychiat, Portland, OR 97329 USA 4.Oregon Hlth & Sci Univ, Adv Imaging Res Ctr, Portland, OR 97329 USA 5.Univ Penn, Perelman Sch Med, Dept Psychiat, Philadelphia, PA 19104 USA 6.Nathan S Kline Inst Psychiat Res, Orangeburg, NY 10962 USA 7.Wayne State Univ, Merrill Palmer Skillman Inst Child & Family Dev, Detroit, MI 48202 USA 8.Wayne State Univ, Dept Pediat, Sch Med, Detroit, MI 48201 USA 9.Child Mind Inst, Ctr Developing Brain, New York, NY 10022 USA 10.Univ Pittsburgh, Dept Psychiat, Sch Med, Pittsburgh, PA 15261 USA |
| 推荐引用方式 GB/T 7714 | Di Martino, Adriana,Fair, Damien A.,Kelly, Clare,et al. Unraveling the Miswired Connectome: A Developmental Perspective[J]. NEURON,2014,83(6):1335-1353. |
| APA | Di Martino, Adriana.,Fair, Damien A..,Kelly, Clare.,Satterthwaite, Theodore D..,Castellanos, F. Xavier.,...&Milham, Michael P..(2014).Unraveling the Miswired Connectome: A Developmental Perspective.NEURON,83(6),1335-1353. |
| MLA | Di Martino, Adriana,et al."Unraveling the Miswired Connectome: A Developmental Perspective".NEURON 83.6(2014):1335-1353. |
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来源：心理研究所
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