Nanotechnology for treating osteoporotic vertebral fractures
文献类型：期刊论文
| 作者 | Gao CX; Wei DL; Yang HL; Chen T; Yang L |
| 刊名 | INTERNATIONAL JOURNAL OF NANOMEDICINE
 |
| 出版日期 | 2015 |
| 卷号 | 10页码:5139-5157 |
| 通讯作者邮箱 | chent@suda.edu.cn ; ylei@suda.edu.cn |
| ISSN号 | 1178-2013 |
| 关键词 | nanomaterials osteoporosis vertebral fracture kyphoplasty bone cement pedicle screw radiopacifier |
| 通讯作者 | Yang, L (reprint author), Robot Microsyst Ctr, Dept Orthopaed Surg, 708 Renmin Rd, Suzhou 215006, Jiangsu, Peoples R China. |
| 产权排序 | [Gao, Chunxia; Wei, Donglei; Yang, Huilin; Yang, Lei] Soochow Univ, Affiliated Hosp 1, Dept Orthopaed Surg, Suzhou, Peoples R China; [Gao, Chunxia; Wei, Donglei; Yang, Huilin; Yang, Lei] Soochow Univ, Affiliated Hosp 1, Inst Orthopaed, Suzhou, Peoples R China; [Chen, Tao] Soochow Univ, Collaborat Innovat Ctr Suzhou Nano Sci & Technol, Robot & Microsyst Ctr, Suzhou, Peoples R China; [Yang, Lei] Chinese Acad Sci, Inst Mech, Lab Nonlinear Mech, Beijing 100080, Peoples R China |
| 中文摘要 | Osteoporosis is a serious public health problem affecting hundreds of millions of aged people worldwide, with severe consequences including vertebral fractures that are associated with significant morbidity and mortality. To augment or treat osteoporotic vertebral fractures, a number of surgical approaches including minimally invasive vertebroplasty and kyphoplasty have been developed. However, these approaches face problems and difficulties with efficacy and long-term stability. Recent advances and progress in nanotechnology are opening up new opportunities to improve the surgical procedures for treating osteoporotic vertebral fractures. This article reviews the improvements enabled by new nanomaterials and focuses on new injectable biomaterials like bone cements and surgical instruments for treating vertebral fractures. This article also provides an introduction to osteoporotic vertebral fractures and current clinical treatments, along with the rationale and efficacy of utilizing nanomaterials to modify and improve biomaterials or instruments. In addition, perspectives on future trends with injectable bone cements and surgical instruments enhanced by nanotechnology are provided. |
| 学科主题 | Science & Technology - Other Topics ; Pharmacology & Pharmacy |
| 类目[WOS] | Nanoscience & Nanotechnology ; Pharmacology & Pharmacy |
| 分类号 | 一类 |
| 研究领域[WOS] | Science & Technology - Other Topics ; Pharmacology & Pharmacy |
| 收录类别 | SCI ; EI |
| 原文出处 | http://dx.doi.org/10.2147/IJN.S85037 |
| 语种 | 英语 |
| WOS记录号 | WOS:000359447500001 |
| 源URL | [http://dspace.imech.ac.cn/handle/311007/55318]  |
| 专题 | 力学研究所_非线性力学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Gao CX,Wei DL,Yang HL,et al. Nanotechnology for treating osteoporotic vertebral fractures[J]. INTERNATIONAL JOURNAL OF NANOMEDICINE,2015,10:5139-5157. |
| APA | Gao CX,Wei DL,Yang HL,Chen T,&Yang L.(2015).Nanotechnology for treating osteoporotic vertebral fractures.INTERNATIONAL JOURNAL OF NANOMEDICINE,10,5139-5157. |
| MLA | Gao CX,et al."Nanotechnology for treating osteoporotic vertebral fractures".INTERNATIONAL JOURNAL OF NANOMEDICINE 10(2015):5139-5157. |
入库方式： OAI收割
来源：力学研究所
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