New Opportunities for High-Field In Vivo MRS in Studying Brain Bioenergetics and Function
文献类型：期刊论文
| 作者 | Zhu, Xiao-Hong1; Du, Fei1; Zhang, Nanyin1; Lei, Hao2; Ugurbil, Kamil1; Chen, Wei1 |
| 刊名 | BRAIN IMAGING AND BEHAVIOR
 |
| 出版日期 | 2008-12-01 |
| 卷号 | 2期号:4页码:232-241 |
| 关键词 | In vivo (31)P MRS In vivo (17)O MRS Brain metabolism Brain function Brain activation Adenosine triphosphate (ATP) ATP production Oxidative phosphorylation Cerebral metabolic rate of oxygen (CMRO(2)) Cerebral metabolic rate of ATP (CMR(ATP)) |
| 英文摘要 | In general, the methodology of magnetic resonance applied in brain research can be divided into two categories: magnetic resonance imaging (MRI) and spectroscopy (MRS). MRI provides rich contrast which is useful for studying brain anatomy, function, behavior and disease. The great merit of in vivo MRS is its ability for noninvasively measuring a variety of cerebral metabolites and neurotransmitters inside a brain. It, therefore, provides an invaluable tool for determining metabolites, chemical reaction rates and bioenergetics, as well as their changes in the human and animal brains. The capability of in vivo MRS is further enhanced at high/ultrahigh magnetic fields because of significant improvements in the detection sensitivity and spectral resolution. Recent progress in technology development has further demonstrated the great potential and promise of in vivo MRS, particularly, in brain research. This article provides a brief review of in vivo MRS methodologies and their applications for determining the cerebral metabolic rates of oxygen, glucose and ATP noninvasively. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Neuroimaging |
| 研究领域[WOS] | Neurosciences & Neurology |
| 关键词[WOS] | MAGNETIC-RESONANCE-SPECTROSCOPY ; OCULAR DOMINANCE COLUMNS ; CEREBRAL METABOLIC-RATE ; HUMAN VISUAL-CORTEX ; GLUCOSE CONSUMPTION ; SENSORY STIMULATION ; 7 T ; OXYGEN ; ACTIVATION ; SIGNAL |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000271090400002 |
| 公开日期 | 2015-10-13 |
| 源URL | [http://ir.wipm.ac.cn/handle/112942/8064]  |
| 专题 | 武汉物理与数学研究所_2011年以前论文发表（包括2011年） |
| 作者单位 | 1.Univ Minnesota, Sch Med, Dept Radiol, Ctr Magnet Resonance Res, Minneapolis, MN 55455 USA 2.Chinese Acad Sci, State Key Lab Magnet Resonance & Mol & Atom Phys, Wuhan Inst Phys & Math, Wuhan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Xiao-Hong,Du, Fei,Zhang, Nanyin,et al. New Opportunities for High-Field In Vivo MRS in Studying Brain Bioenergetics and Function[J]. BRAIN IMAGING AND BEHAVIOR,2008,2(4):232-241. |
| APA | Zhu, Xiao-Hong,Du, Fei,Zhang, Nanyin,Lei, Hao,Ugurbil, Kamil,&Chen, Wei.(2008).New Opportunities for High-Field In Vivo MRS in Studying Brain Bioenergetics and Function.BRAIN IMAGING AND BEHAVIOR,2(4),232-241. |
| MLA | Zhu, Xiao-Hong,et al."New Opportunities for High-Field In Vivo MRS in Studying Brain Bioenergetics and Function".BRAIN IMAGING AND BEHAVIOR 2.4(2008):232-241. |
入库方式： OAI收割
来源：武汉物理与数学研究所
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