Novel Ti4+-chelated magnetic nanostructured affinity microspheres containing N-methylene phosphonic chitosan for highly selective enrichment and rapid separation of phosphopeptides
文献类型：期刊论文
| 作者 | Wang, Zhi-Gang ; Zhang, Ji-Lin ; Sun, De-Hui ; Ni,Jia-Zan |
| 刊名 | journal of materials chemistry b
 |
| 出版日期 | 2014 |
| 卷号 | 2期号:39页码:6886-6892 |
| 关键词 | CORE-SHELL MICROSPHERES MASS-SPECTROMETRY NANOCRYSTAL CLUSTERS NANOPARTICLES PHOSPHOPROTEOMICS PHOSPHORYLATION FABRICATION PROTEOMICS PROTEINS HYBRID |
| 通讯作者 | zhang,jl |
| 英文摘要 | magnetic composite particles immobilized with metal affinity ions show high potential in the phosphoproteome mass-spectrometric (ms) analysis. however, the preparation of this kind of material still suffers from a complicated synthesis procedure and high cost. in this work, the magnetic nanostructured composite microspheres (mpcs) incorporated into n-methylene phosphonic chitosan were first fabricated via a facile one-pot synthesis strategy and titanium ions (ti4+) were subsequently immobilized onto the mpcs to form mpcs-ti4+ affinity particles. the uniform spherical mpcs-ti4+ affinity particles with abundant chelated titanium ions have a particle size distribution between 126 nm and 280 nm, and they display superparamagnetism with a saturation magnetization (m-s) value of 44.75 emu g(-1). the amount of the immobilized ti4+ ions was estimated to be 11.6 wt% by eds. the mpcs-ti4+ exhibited excellent dispersibility in aqueous solution, high affinity selectivity for phosphopeptides and quite fast magnetic separation within 10 s as well as good reusability. thus, the prepared magnetic mpcs-ti4+ nanostructured affinity materials will possess great potential in phosphoproteome research. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000342856400022 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/56219]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Wang, Zhi-Gang,Zhang, Ji-Lin,Sun, De-Hui,et al. Novel Ti4+-chelated magnetic nanostructured affinity microspheres containing N-methylene phosphonic chitosan for highly selective enrichment and rapid separation of phosphopeptides[J]. journal of materials chemistry b,2014,2(39):6886-6892. |
| APA | Wang, Zhi-Gang,Zhang, Ji-Lin,Sun, De-Hui,&Ni,Jia-Zan.(2014).Novel Ti4+-chelated magnetic nanostructured affinity microspheres containing N-methylene phosphonic chitosan for highly selective enrichment and rapid separation of phosphopeptides.journal of materials chemistry b,2(39),6886-6892. |
| MLA | Wang, Zhi-Gang,et al."Novel Ti4+-chelated magnetic nanostructured affinity microspheres containing N-methylene phosphonic chitosan for highly selective enrichment and rapid separation of phosphopeptides".journal of materials chemistry b 2.39(2014):6886-6892. |
入库方式： OAI收割
来源：长春应用化学研究所
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