Multifunctional Core-Shell Structured Nanocarriers for Synchronous Tumor Diagnosis and Treatment In Vivo
文献类型：期刊论文
| 作者 | Chen, Yin-Yin ; Ma, Ping-An ; Yang, Dong-Mei ; Wu,Yuan ; Dai,Yun-Lu ; Li,Chun-Xia ; Lin,Jun |
| 刊名 | chemistry-an asian journal
 |
| 出版日期 | 2014 |
| 卷号 | 9期号:2页码:506-513 |
| 关键词 | UP-CONVERSION NANOPARTICLES MESOPOROUS SILICA NANOPARTICLES CONTROLLED DRUG-DELIVERY UPCONVERTING NANOPARTICLES FLUORESCENT NANOPARTICLES OPTICAL SPECTROSCOPY PHOTODYNAMIC THERAPY NANOCRYSTALS NANOPROBES LUMINESCENCE |
| 通讯作者 | chen,yy |
| 英文摘要 | multifunctional, mesoporous, silica-coated upconversion luminescent/magnetic nagdf4:yb/er@nagdf4:yb@msio(2)peg (referred to as ucnps; peg=polyethylene glycol) nanocomposites were fabricated through a phase-transfer-assisted surfactant-templating coating process, followed by hydrophilic polymer (peg) functionalization to improve the stability and biocompatibility. the ucnp core imparts the nanomaterials with luminescence and magnetic properties for simultaneous upconversion optical and magnetic resonance (mr) imaging, whereas the mesoporous shell affords the nanomaterials the ability to load the anticancer drug doxorubicin. proof-of-principle in vitro and in vivo experiments are presented to demonstrate that the resultant composite nanomaterials can serve as nanotheranostics for synchronous upconversion luminescence/mr dual modal imaging and anticancer drug delivery; this finally realizes the integration of diagnostics and the treatment of cancers. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000331088600018 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/56238]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Chen, Yin-Yin,Ma, Ping-An,Yang, Dong-Mei,et al. Multifunctional Core-Shell Structured Nanocarriers for Synchronous Tumor Diagnosis and Treatment In Vivo[J]. chemistry-an asian journal,2014,9(2):506-513. |
| APA | Chen, Yin-Yin.,Ma, Ping-An.,Yang, Dong-Mei.,Wu,Yuan.,Dai,Yun-Lu.,...&Lin,Jun.(2014).Multifunctional Core-Shell Structured Nanocarriers for Synchronous Tumor Diagnosis and Treatment In Vivo.chemistry-an asian journal,9(2),506-513. |
| MLA | Chen, Yin-Yin,et al."Multifunctional Core-Shell Structured Nanocarriers for Synchronous Tumor Diagnosis and Treatment In Vivo".chemistry-an asian journal 9.2(2014):506-513. |
入库方式： OAI收割
来源：长春应用化学研究所
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