Immobilizing PEO-PPO-PEO triblock copolymers on hydrophobic surfaces and its effect on protein and platelet: A combined study using QCM-D and DPI
文献类型：期刊论文
| 作者 | Jin, Jing ; Huang, Fujian ; Hu, Yu ; Jiang,Wei ; Ji,Xiangling ; Liang,Haojun ; Yin,Jinghua |
| 刊名 | colloids and surfaces b-biointerfaces
 |
| 出版日期 | 2014 |
| 卷号 | 123页码:892-899 |
| 关键词 | QUARTZ-CRYSTAL MICROBALANCE DUAL-POLARIZATION INTERFEROMETRY SELF-ASSEMBLED MONOLAYERS ADSORPTION BEHAVIOR POLYETHYLENE OXIDE BLOCK-COPOLYMERS LYSOZYME ADSORPTION ALBUMIN ADSORPTION PLASMA-PROTEINS SOLID-SURFACES |
| 通讯作者 | jiang,w |
| 英文摘要 | dual polarization interferometry was used to monitor the immobilization dynamics of four pluronics on hydrophobic surfaces and to elucidate the effect of pluronic conformation on protein adsorption. the proportion of hydrophobic chain segments and not the length of the hydrophobic chain can influence the chain densities of the pluronics. the immobilized densities of the pluronics resulted from competition between the hydration of polyethylene oxide (peo) in the aqueous solution and the hydrophobic interaction of polypropylene oxide on the substrate. p-123 obtained the largest graft mass (2.89 +/- 0.25 ng/mm(2)) because of the dominant effect of hydrophobic interactions. hydrophobic segments of p-123 were anchored slowly and step-wise on the c18 substrate. p-123 exhibited the largest hydrophobic chain segment proportion (propylene oxide/ethylene oxide =3.63) and formed a brush chain conformation, indicating excellent protein and platelet resistance. the result of quartz crystal microbalance with dissipation further confirmed that the peo conformation in p-123 on the substrate exhibited a relatively extended brush chain, and that l-35 showed relatively loose and pancake-like structures. the peo in p-123 regulated the conformation to maintain the native conformation and resist the adsorption of bovine serum albumin (bsa). thus, the hemocompatibilities of the immobilized pluronics were influenced by the proportion of hydrophobic chain segments and their peo conformations. crown copyright (c) 2014 published by elsevier b.v. all rights reserved. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000347580500112 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/57203]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Jin, Jing,Huang, Fujian,Hu, Yu,et al. Immobilizing PEO-PPO-PEO triblock copolymers on hydrophobic surfaces and its effect on protein and platelet: A combined study using QCM-D and DPI[J]. colloids and surfaces b-biointerfaces,2014,123:892-899. |
| APA | Jin, Jing.,Huang, Fujian.,Hu, Yu.,Jiang,Wei.,Ji,Xiangling.,...&Yin,Jinghua.(2014).Immobilizing PEO-PPO-PEO triblock copolymers on hydrophobic surfaces and its effect on protein and platelet: A combined study using QCM-D and DPI.colloids and surfaces b-biointerfaces,123,892-899. |
| MLA | Jin, Jing,et al."Immobilizing PEO-PPO-PEO triblock copolymers on hydrophobic surfaces and its effect on protein and platelet: A combined study using QCM-D and DPI".colloids and surfaces b-biointerfaces 123(2014):892-899. |
入库方式： OAI收割
来源：长春应用化学研究所
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