A graphene quantum dot-based method for the highly sensitive and selective fluorescence turn on detection of biothiols
文献类型：期刊论文
| 作者 | Wu, Zhenzhu ; Li, Wenying ; Chen, Jian ; Yu,Cong |
| 刊名 | talanta
 |
| 出版日期 | 2014 |
| 卷号 | 119期号:4页码:538-543 |
| 关键词 | LABEL-FREE COLORIMETRIC PROBES EMERGENT NANOLIGHTS GOLD NANOPARTICLES MASS-SPECTROMETRY AQUEOUS-SOLUTIONS CARBON NANODOTS GLUTATHIONE CYSTEINE HOMOCYSTEINE |
| 通讯作者 | yu,c |
| 英文摘要 | a facile assay method for the highly sensitive and selective sensing of biothiols based on graphene quantum dots (gqds) has been developed. gqds emitted strong blue fluorescence in an aqueous buffer solution. it was observed that mercury(ii) ions could efficiently bind and quench the fluorescence of the gqds. when a biothiol compound (glutathione, cysteine, or homocysteine) was added to the assay mixture of gqds and mercury(ii), it bound to mercury(ii) ions. hg2+-gqd complex dissociated, and a fluorescence turn-on signal was detected. the emission intensity changes of the gqds could be directly related to the amount of biothiol added to the assay solution. the assay is highly sensitive, the limits of detection clod) for gsh, cys and hcy were 5 nm, 2.5 nm and 5 nm, respectively. the assay is also highly selective, a number of amino acids and proteins were tested, and little interference was observed. in addition, gsh standard recovery in serum samples was also demonstrated. we envision that our assay method could facilitate the biothiol quantification related biological and biomedical research. (c) 2013 elsevier b.v. all rights reserved. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000331670700077 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/57324]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Wu, Zhenzhu,Li, Wenying,Chen, Jian,et al. A graphene quantum dot-based method for the highly sensitive and selective fluorescence turn on detection of biothiols[J]. talanta,2014,119(4):538-543. |
| APA | Wu, Zhenzhu,Li, Wenying,Chen, Jian,&Yu,Cong.(2014).A graphene quantum dot-based method for the highly sensitive and selective fluorescence turn on detection of biothiols.talanta,119(4),538-543. |
| MLA | Wu, Zhenzhu,et al."A graphene quantum dot-based method for the highly sensitive and selective fluorescence turn on detection of biothiols".talanta 119.4(2014):538-543. |
入库方式： OAI收割
来源：长春应用化学研究所
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