A fluorescence glucose sensor based on pH induced conformational switch of i-motif DNA
文献类型：期刊论文
| 作者 | Ke, Qingqing ; Zheng, Yu ; Yang, Fan ; Zhang,Hanchang ; Yang,Xiurong |
| 刊名 | talanta
 |
| 出版日期 | 2014 |
| 卷号 | 129期号:73页码:539-544 |
| 关键词 | COLORIMETRIC DETECTION QUANTUM DOTS NANOPARTICLES BIOSENSOR NANOCLUSTERS NANOMACHINE MACHINES PLATFORM |
| 通讯作者 | zhang,hc |
| 英文摘要 | a facile fluorescence biosensor for the detection of glucose is proposed based on the ph-induced conformational switch of i-motif dna in this paper. glucose can be oxidized by oxygen (o-2) in the presence of glucose oxidase (god), and the generated gluconic acid can decrease the ph value of the solution and then induce the fluorophore- and quencher-labeled cytosine-rich single-stranded dna to fold into a close-packed i-motif structure. as a result, the fluorescence quenching occurs because of the resonance energy transfer between fluorophore and quencher. based on this working principle, the concentration of glucose can be detected by the decrease of fluorescence density. under the optimal experimental conditions, the assay shows a linear response range of 5-100 mu m for the glucose concentration with a detection limit of 4 mu m. this glucose biosensor was applied to determine glucose in real samples successfully, suggesting its potential in the practical applicability. (c) 2014 elsevier b.v. all rights reserved. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2015-10-27 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/57326]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Ke, Qingqing,Zheng, Yu,Yang, Fan,et al. A fluorescence glucose sensor based on pH induced conformational switch of i-motif DNA[J]. talanta,2014,129(73):539-544. |
| APA | Ke, Qingqing,Zheng, Yu,Yang, Fan,Zhang,Hanchang,&Yang,Xiurong.(2014).A fluorescence glucose sensor based on pH induced conformational switch of i-motif DNA.talanta,129(73),539-544. |
| MLA | Ke, Qingqing,et al."A fluorescence glucose sensor based on pH induced conformational switch of i-motif DNA".talanta 129.73(2014):539-544. |
入库方式： OAI收割
来源：长春应用化学研究所
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