中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Fabricating antigen recognition and anti-bioadhesion polymeric surface via a photografting polymerization strategy

文献类型:期刊论文

作者Song, Lingjie ; Zhao, Jie ; Jin, Jing ; Ma,Jiao ; Liu,Jingchuan ; Luan,Shifang ; Yin,Jinghua
刊名materials science & engineering c-biomimetic and supramolecular systems
出版日期2014
卷号36期号:7页码:57-64
关键词INDUCED GRAFT-POLYMERIZATION POLYETHYLENE-GLYCOL ACRYLATE N-VINYL PYRROLIDONE PROTEIN IMMOBILIZATION 2-METHACRYLOYLOXYETHYL PHOSPHORYLCHOLINE COVALENT FUNCTIONALIZATION ZWITTERIONIC POLYMER PHOSPHOLIPID POLYMER DRUG-DELIVERY ADSORPTION
通讯作者luan,sf
英文摘要a polymeric platform for immunodiagnostic bioassay was constructed based on biostable polymeric support and two functional monomers, low-fouling methacryloyloxyethyl phosphorylcholine (mpc) and acrylic acid (aac), by a photografting polymerization approach. covalent binding of antibody to paac chains was achieved by activating carboxyl with nhs/edc partner. the resultant surface showed obvious suppression of nonspecific protein adsorption and platelet adhesion relative to the control sample, exhibiting good anti-bioadhesion performances. based on the polymer-supported matrix, a highly sensitive antibody-antigen specific recognition was confirmed in both native plasma and diluted human plasma due to the enhanced antibody loading capacity and lowered bioadhesion as compared to the reference. (c) 2013 elsevier b.v. all rights reserved.
收录类别SCI
语种英语
WOS记录号WOS:000331509300009
源URL[http://ir.ciac.jl.cn/handle/322003/57374]  
专题长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式
GB/T 7714
Song, Lingjie,Zhao, Jie,Jin, Jing,et al. Fabricating antigen recognition and anti-bioadhesion polymeric surface via a photografting polymerization strategy[J]. materials science & engineering c-biomimetic and supramolecular systems,2014,36(7):57-64.
APA Song, Lingjie.,Zhao, Jie.,Jin, Jing.,Ma,Jiao.,Liu,Jingchuan.,...&Yin,Jinghua.(2014).Fabricating antigen recognition and anti-bioadhesion polymeric surface via a photografting polymerization strategy.materials science & engineering c-biomimetic and supramolecular systems,36(7),57-64.
MLA Song, Lingjie,et al."Fabricating antigen recognition and anti-bioadhesion polymeric surface via a photografting polymerization strategy".materials science & engineering c-biomimetic and supramolecular systems 36.7(2014):57-64.

入库方式: OAI收割

来源:长春应用化学研究所

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