Direct Analysis in Real Time-Mass Spectrometry for the Rapid Detection of Metabolites of Aconite Alkaloids in Intestinal Bacteria
文献类型：期刊论文
| 作者 | Li, Xue ; Hou, Guangyue ; Xing, Junpeng ; Song,Rengrui ; Liu,Zhiqiang ; Liu,Shuying |
| 刊名 | journal of the american society for mass spectrometry
 |
| 出版日期 | 2014 |
| 卷号 | 25期号:12页码:2181-2184 |
| 关键词 | RADIX-ACONITI RAT IONIZATION PREPARATA |
| 通讯作者 | song,fr |
| 英文摘要 | in the present work, direct analysis of real time ionization combined with multi-stage tandem mass spectrometry (dart-msn) was used to investigate the metabolic profile of aconite alkaloids in rat intestinal bacteria. a total of 36 metabolites from three aconite alkaloids were identified by using dart-msn, and the feasibility of quantitative analysis of these analytes was examined. key parameters of the dart ion source, such as helium gas temperature and pressure, the source-to-ms distance, and the speed of the autosampler, were optimized to achieve high sensitivity, enhance reproducibility, and reduce the occurrence of fragmentation. the instrument analysis time for one sample can be less than 10 s for this method. compared with esi-ms and uplc-ms, the dart-ms is more efficient for directly detecting metabolic samples, and has the advantage of being a simple, high-speed, high-throughput method. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2015-10-27 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/57389]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Li, Xue,Hou, Guangyue,Xing, Junpeng,et al. Direct Analysis in Real Time-Mass Spectrometry for the Rapid Detection of Metabolites of Aconite Alkaloids in Intestinal Bacteria[J]. journal of the american society for mass spectrometry,2014,25(12):2181-2184. |
| APA | Li, Xue,Hou, Guangyue,Xing, Junpeng,Song,Rengrui,Liu,Zhiqiang,&Liu,Shuying.(2014).Direct Analysis in Real Time-Mass Spectrometry for the Rapid Detection of Metabolites of Aconite Alkaloids in Intestinal Bacteria.journal of the american society for mass spectrometry,25(12),2181-2184. |
| MLA | Li, Xue,et al."Direct Analysis in Real Time-Mass Spectrometry for the Rapid Detection of Metabolites of Aconite Alkaloids in Intestinal Bacteria".journal of the american society for mass spectrometry 25.12(2014):2181-2184. |
入库方式： OAI收割
来源：长春应用化学研究所
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