Ultrahigh-performance liquid chromatography/tandem mass spectrometry method for evaluating enzyme activity and screening inhibitors of cyclooxygenase-2
文献类型：期刊论文
| 作者 | Zhu, Hongbin ; Zhuang, Xiaoyu ; Liu, Shu ; Pi,Zifeng ; Song,Fengrui ; Lin,Na ; Liu,Zhiqiang |
| 刊名 | rapid communications in mass spectrometry
 |
| 出版日期 | 2014 |
| 卷号 | 28期号:16页码:1792-1800 |
| 关键词 | LC-MS/MS BIOACTIVE LIPIDS DERIVATIZATION REAGENT ARACHIDONIC-ACID EICOSANOIDS PROSTAGLANDINS QUANTITATION METABOLITES CANCER |
| 通讯作者 | song,fr |
| 英文摘要 | rationale: prostaglandin e-2 is an important biomarker in many biological systems. the development of sensitive and reliable analytical methods for monitoring pge(2) contents in various samples is of great interest. here we developed an improved method for evaluating the enzyme activity and screening cox-2 inhibitors using ultrahigh-performance liquid chromatography/tandem mass spectrometry (uplc/ms/ms) combined with pge(2) derivatization. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2015-10-27 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/57426]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Zhu, Hongbin,Zhuang, Xiaoyu,Liu, Shu,et al. Ultrahigh-performance liquid chromatography/tandem mass spectrometry method for evaluating enzyme activity and screening inhibitors of cyclooxygenase-2[J]. rapid communications in mass spectrometry,2014,28(16):1792-1800. |
| APA | Zhu, Hongbin.,Zhuang, Xiaoyu.,Liu, Shu.,Pi,Zifeng.,Song,Fengrui.,...&Liu,Zhiqiang.(2014).Ultrahigh-performance liquid chromatography/tandem mass spectrometry method for evaluating enzyme activity and screening inhibitors of cyclooxygenase-2.rapid communications in mass spectrometry,28(16),1792-1800. |
| MLA | Zhu, Hongbin,et al."Ultrahigh-performance liquid chromatography/tandem mass spectrometry method for evaluating enzyme activity and screening inhibitors of cyclooxygenase-2".rapid communications in mass spectrometry 28.16(2014):1792-1800. |
入库方式： OAI收割
来源：长春应用化学研究所
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