Pulmonary Drugs and Genes Delivery Systems for Lung Disease Treatment
文献类型：期刊论文
| 作者 | Xu, Caina ; Tian, Huayu ; Chen, Xuesi |
| 刊名 | chinese journal of chemistry
 |
| 出版日期 | 2014 |
| 卷号 | 32期号:1页码:13-21 |
| 关键词 | LARGE POROUS PARTICLES LIPID-COATED NANOPARTICLES LARGE PLGA MICROPARTICLES AEROSOL DELIVERY IN-VIVO INHALATION DELIVERY PEI-P53 COMPLEXES TARGETED DELIVERY PDNA/PEI COMPLEXES HEALTHY-VOLUNTEERS |
| 通讯作者 | tian,hy |
| 英文摘要 | pulmonary drugs and genes delivery systems have become an attractive approach in the treatment of lung diseases with the advantages of minimal drug loss, precise quantization, high local drugs concentration and low side effects. however, special attention should be paid to the biological barriers of the lung. the delivery systems need to be designed carefully in order to overcome these biological barriers and maximize the drugs and genes deposition to the lungs. pulmonary drugs and genes delivery systems can offer some encouraging results for delivering drugs and genes to the lungs. specifically, some lipid-based and polymer-based delivery systems could control and sustain the release of drugs and genes with minimal or negligible toxicity. this review focuses on the latest development of pulmonary delivery of drugs and genes for the treatment of various lung diseases. the barriers to the lung, the delivery devices, the route of the administration and the delivery systems for drugs and genes pulmonary delivery are described. based on the rapid development of clinical requirement, novel approaches using delivery systems for pulmonary delivery drugs and genes need to be constructed, which is believed to play an important role in the therapy of lung diseases in the future. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2015-10-27 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/57510]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Xu, Caina,Tian, Huayu,Chen, Xuesi. Pulmonary Drugs and Genes Delivery Systems for Lung Disease Treatment[J]. chinese journal of chemistry,2014,32(1):13-21. |
| APA | Xu, Caina,Tian, Huayu,&Chen, Xuesi.(2014).Pulmonary Drugs and Genes Delivery Systems for Lung Disease Treatment.chinese journal of chemistry,32(1),13-21. |
| MLA | Xu, Caina,et al."Pulmonary Drugs and Genes Delivery Systems for Lung Disease Treatment".chinese journal of chemistry 32.1(2014):13-21. |
入库方式： OAI收割
来源：长春应用化学研究所
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