Shape-Persistent, Thermoresponsive Polypeptide Brushes Prepared by Vapor Deposition Surface-Initiated Ring-Opening Polymerization of alpha-Amino Acid N-Carboxyanhydrides
文献类型：期刊论文
| 作者 | Shen, Yong1; Desseaux, Solenne2,3; Aden, Bethany4,5; Lokitz, Bradley S.6; Kilbey, S. Michael, II4,5; Li, Zhibo1; Klok, Harm-Anton2,3 |
| 刊名 | MACROMOLECULES
 |
| 出版日期 | 2015-04-28 |
| 卷号 | 48期号:8页码:2399-2406 |
| 英文摘要 | Surface-grafting thermoresponsive polymers allows the preparation of thin polymer brush coatings with surface properties that can be manipulated by variation of temperature. In most instances, thermoresponsive polymer brushes are produced using polymers that dehydrate and collapse above a certain temperature. This report presents the preparation and properties of polymer brushes that show thermoresponsive surface properties, yet are shape-persistent in that they do not undergo main chain collapse. The polymer brushes presented here are obtained via vapor deposition surface-initiated ring-opening polymerization (SI-ROP) of gamma-di- or tri(ethylene glycol)-modified glutamic acid N-carboxyanhydrides. Vapor deposition SI-ROP of gamma-di- or tri(ethylene glycol)-modified l- or d-glutamic acid N-carboxyanhydrides affords helical surface-tethered polymer chains that do not show any changes in secondary structure between 10 and 70 degrees C. QCM-D experiments, however, revealed significant dehydration of poly(gamma-(2-(2-methoxyethoxy)ethyl)-l-glutamate) (poly(L-EG(2)-Glu)) brushes upon heating from 10 to 40 degrees C. At the same time, AFM and ellipsometry studies did not reveal significant variations in film thickness over this temperature range, which is consistent with the shape-persistent nature of these polypeptide brushes and indicates that the thermoresponsiveness of the films is primarily due to hydration and dehydration of the oligo(ethylene glycol) side chains. The results presented here illustrate the potential of surface-initiated NCA ring-opening polymerization to generate densely grafted assemblies of polymer chains that possess well-defined secondary structures and tunable surface properties. These polypeptide brushes complement their conformationally unordered counterparts that can be generated via surface-initiated polymerization of vinyl-type monomers and represent another step forward to biomimetic surfaces and interfaces. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2015-11-02 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/28077]  |
| 专题 | 化学研究所_高分子物理与化学实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci BNLMS, Beijing 100190, Peoples R China 2.Ecole Polytech Fed Lausanne, Inst Mat, CH-1015 Lausanne, Switzerland 3.Ecole Polytech Fed Lausanne, Inst Sci & Ingn Chim, Lab Polymeres, CH-1015 Lausanne, Switzerland 4.Univ Tennessee, Dept Chem, Knoxville, TN 37996 USA 5.Univ Tennessee, Dept Chem & Biomol Engn, Knoxville, TN 37996 USA 6.Oak Ridge Natl Lab, Ctr Nanophase Mat Sci, Oak Ridge, TN 37831 USA |
| 推荐引用方式 GB/T 7714 | Shen, Yong,Desseaux, Solenne,Aden, Bethany,et al. Shape-Persistent, Thermoresponsive Polypeptide Brushes Prepared by Vapor Deposition Surface-Initiated Ring-Opening Polymerization of alpha-Amino Acid N-Carboxyanhydrides[J]. MACROMOLECULES,2015,48(8):2399-2406. |
| APA | Shen, Yong.,Desseaux, Solenne.,Aden, Bethany.,Lokitz, Bradley S..,Kilbey, S. Michael, II.,...&Klok, Harm-Anton.(2015).Shape-Persistent, Thermoresponsive Polypeptide Brushes Prepared by Vapor Deposition Surface-Initiated Ring-Opening Polymerization of alpha-Amino Acid N-Carboxyanhydrides.MACROMOLECULES,48(8),2399-2406. |
| MLA | Shen, Yong,et al."Shape-Persistent, Thermoresponsive Polypeptide Brushes Prepared by Vapor Deposition Surface-Initiated Ring-Opening Polymerization of alpha-Amino Acid N-Carboxyanhydrides".MACROMOLECULES 48.8(2015):2399-2406. |
入库方式： OAI收割
来源：化学研究所
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