DNA Catalyzed Dithioacetalization in Water
文献类型：期刊论文
| 作者 | Wang Changhao; Li Yinghao; Jia Guoqing; Lu Shengmei; Liu Yan; Li Can |
| 刊名 | acta chimica sinica
 |
| 出版日期 | 2013-01-15 |
| 卷号 | 71期号:1页码:36-39 |
| 关键词 | double-stranded DNA herring sperm catalysis dithioacetalization water medium phosphate group |
| 英文摘要 | the most popular hypothesis of precellular life is the "rna world", which is utilizing rna as both genetic as well as catalytic material. the chemical similarity between rna and dna leads researchers to investigate whether dna has the catalytic function, although dna is commonly viewed as a genetic carrier with a ubiquitous double-stranded architecture in living world. nevertheless, the catalytic dna has not been discovered in nature to date. in recent years, the catalytic function of dna in nonbiological applications has aroused much interest to chemists in chemical synthesis such as dna-templated organic synthesis and dna-based asymmetric catalysis. however, the investigation of dna as a direct catalyst for organic synthesis is largely elusive. here we report that double-stranded dna from herring sperm can catalyze the dithioacetalization in water for a wide range of aldehydes under mild reaction conditions. it is proposed that the phosphate groups of dna together with the duplex architecture are responsible for the catalytic reaction. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, multidisciplinary |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | chemoselective dithioacetalization ; carbonyl-compounds ; organic-synthesis ; efficient catalyst ; aldol reaction ; aqueous-media ; rna world ; acid ; thioacetalization ; aldehydes |
| 收录类别 | SCI ; CCR |
| 语种 | 英语 |
| WOS记录号 | WOS:000315605300003 |
| 公开日期 | 2015-11-10 |
| 源URL | [http://159.226.238.44/handle/321008/137473]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Catalysis, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang Changhao,Li Yinghao,Jia Guoqing,et al. DNA Catalyzed Dithioacetalization in Water[J]. acta chimica sinica,2013,71(1):36-39. |
| APA | Wang Changhao,Li Yinghao,Jia Guoqing,Lu Shengmei,Liu Yan,&Li Can.(2013).DNA Catalyzed Dithioacetalization in Water.acta chimica sinica,71(1),36-39. |
| MLA | Wang Changhao,et al."DNA Catalyzed Dithioacetalization in Water".acta chimica sinica 71.1(2013):36-39. |
入库方式： OAI收割
来源：大连化学物理研究所
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