Preparation and application of hollow molecularly imprinted polymers with a super-high selectivity to the template protein
文献类型：期刊论文
| 作者 | Chen, Yang1; He, Xi-Wen1; Mao, Jie1; Li, Wen-You1; Zhang, Yu-Kui1,2,3 |
| 刊名 | journal of separation science
 |
| 出版日期 | 2013-10-01 |
| 卷号 | 36期号:20页码:3449-3456 |
| 关键词 | Etching Hollow core Lysozyme Molecularly imprinted polymers Protein separation |
| 英文摘要 | protein-imprinted polymers with hollow cores that have a super-high imprinting factor were prepared by etching the core of the surface-imprinted polymers that used silica particles as the support. lysozyme as template was modified onto the surface of silica particles by a covalent method, and after polymerization and the removal of template molecules, channels through the polymer layer were formed, which allowed a single-protein molecule to come into the hollow core and attach to the binding sites inside the polymer layer. the adsorption experiments demonstrated that the hollow imprinted polymers had an extremely high binding capacity and selectivity, and thus a super-high imprinting factor was obtained. the as-prepared imprinted polymers were used to separate the template lysozyme from egg white successfully, indicating its high selectivity and potential application in the field of separation of protein from real samples. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, analytical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | silica nanoparticles ; surface ; recognition ; antibodies ; doxorubicin ; receptors ; membrane ; strategy ; capture |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000325482500020 |
| 公开日期 | 2015-11-10 |
| 源URL | [http://159.226.238.44/handle/321008/137593]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Nankai Univ, Dept Chem, State Key Lab Med Chem Biol, Tianjin 300071, Peoples R China 2.Synerget Innovat Ctr Chem Sci & Engn Tianjin, Tianjin, Peoples R China 3.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Dalian, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Yang,He, Xi-Wen,Mao, Jie,et al. Preparation and application of hollow molecularly imprinted polymers with a super-high selectivity to the template protein[J]. journal of separation science,2013,36(20):3449-3456. |
| APA | Chen, Yang,He, Xi-Wen,Mao, Jie,Li, Wen-You,&Zhang, Yu-Kui.(2013).Preparation and application of hollow molecularly imprinted polymers with a super-high selectivity to the template protein.journal of separation science,36(20),3449-3456. |
| MLA | Chen, Yang,et al."Preparation and application of hollow molecularly imprinted polymers with a super-high selectivity to the template protein".journal of separation science 36.20(2013):3449-3456. |
入库方式： OAI收割
来源：大连化学物理研究所
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