Study of the peak variance in isocratic and gradient liquid chromatography using the transport model
文献类型：期刊论文
| 作者 | Hao, Weiqiang1; Di, Bin2; Chen, Qiang1; Wang, Junde3; Yang, Yongbin1; Sun, Xiaoli1 |
| 刊名 | journal of chromatography a
 |
| 出版日期 | 2013-06-21 |
| 卷号 | 1295页码:67-81 |
| 关键词 | Gradient elution Liquid chromatography Transport model Plate height |
| 英文摘要 | the expressions accounting for the peak variance in isocratic and gradient liquid chromatography is derived from the transport model. in mathematical treatments, the dwelling time is taken into account, and the type of solvent strength, gradient profile and the variation of plate height (h) with mobile phase composition (phi) is not specified. by applying a coordinate transformation, the transport model is solved by using the laplace transform approach. a plate height equation that is suited for both isocratic and gradient elution is obtained. based on this equation, the plate height equations for any combination of stepwise and linear gradients are derived. these equations will be algebraic when the solvent strength is linear and the h-phi plot is parabolic. the plate height equations for single stepwise, single linear and the ladder-like gradients are also given. (c) 2013 elsevier b.v. all rights reserved. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 类目[WOS] | biochemical research methods ; chemistry, analytical |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry |
| 关键词[WOS] | mass-transfer kinetics ; elution chromatography ; ion-exchange ; compression factor ; frontal analysis ; linear gradient ; ideal model ; phase ; separations ; proteins |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000320294000007 |
| 公开日期 | 2015-11-10 |
| 源URL | [http://159.226.238.44/handle/321008/137666]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Nanjing Univ, High Tech Res Inst, Changzhou 213164, Peoples R China 2.China Pharmaceut Univ, Dept Pharmaceut Anal, Nanjing 210009, Jiangsu, Peoples R China 3.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hao, Weiqiang,Di, Bin,Chen, Qiang,et al. Study of the peak variance in isocratic and gradient liquid chromatography using the transport model[J]. journal of chromatography a,2013,1295:67-81. |
| APA | Hao, Weiqiang,Di, Bin,Chen, Qiang,Wang, Junde,Yang, Yongbin,&Sun, Xiaoli.(2013).Study of the peak variance in isocratic and gradient liquid chromatography using the transport model.journal of chromatography a,1295,67-81. |
| MLA | Hao, Weiqiang,et al."Study of the peak variance in isocratic and gradient liquid chromatography using the transport model".journal of chromatography a 1295(2013):67-81. |
入库方式： OAI收割
来源：大连化学物理研究所
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