Possible cage-like nanostructures formed by amino acids
文献类型：期刊论文
| 作者 | Wang, Cui-hong1,2,3; Wu, Qi1; Fan, Wen-jie4; Zhang, Rui-qin1; Lin, Zijing2,5 |
| 刊名 | organic & biomolecular chemistry
 |
| 出版日期 | 2012 |
| 卷号 | 10期号:26页码:5049-5054 |
| 英文摘要 | we report possible cage-like nanostructures formed by a representative amino acid, serine octamers and decamers, determined by binding energy calculations and molecular dynamic simulations using the density functional tight-binding method. we used the l-handed serine to construct complex conformers linked by hydrogen bonds. we found the structures linked by -cooh center dot center dot center dot o=c- to be the most stable conformers and the calculation of the vibrational modes of complexes further illustrated this result. we attempted to apply our cage-like structures to the delivery of c-20 and cycloserine as model molecules. our results may shed light on the design of cage-like biocompatible complexes for drug delivery. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, organic |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | assembling peptide nanotubes ; drug-delivery ; molecular-dynamics ; conformational profile ; hydrogen-bonds ; design ; ion ; simulations ; phenylalanine ; energetics |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000305191000007 |
| 公开日期 | 2015-11-10 |
| 源URL | [http://159.226.238.44/handle/321008/138078]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.City Univ Hong Kong, Dept Phys & Mat Sci, Hong Kong, Hong Kong, Peoples R China 2.Univ Sci & Technol China, Dept Phys, Hefei 230026, Peoples R China 3.USTC CityU Joint Adv Res Ctr, Suzhou 215123, Peoples R China 4.Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Mol Dynam, Dalian 116023, Peoples R China 5.Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, Hefei 230026, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Cui-hong,Wu, Qi,Fan, Wen-jie,et al. Possible cage-like nanostructures formed by amino acids[J]. organic & biomolecular chemistry,2012,10(26):5049-5054. |
| APA | Wang, Cui-hong,Wu, Qi,Fan, Wen-jie,Zhang, Rui-qin,&Lin, Zijing.(2012).Possible cage-like nanostructures formed by amino acids.organic & biomolecular chemistry,10(26),5049-5054. |
| MLA | Wang, Cui-hong,et al."Possible cage-like nanostructures formed by amino acids".organic & biomolecular chemistry 10.26(2012):5049-5054. |
入库方式： OAI收割
来源：大连化学物理研究所
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