Separation of enantiomers of drugs by capillary electrophoresis - V. Hydroxypropyl-alpha-cyclodextrin as chiral solvating agent
文献类型：期刊论文
| 作者 | Koppenhoefer, B; Epperlein, U; Schlunk, R; Zhu, XF; Lin, BC |
| 刊名 | journal of chromatography a
 |
| 出版日期 | 1998-01-09 |
| 卷号 | 793期号:1页码:153-164 |
| 关键词 | enantiomer separation mobile phase separation drugs cyclodextrins chiral |
| 英文摘要 | in an extended chiral drug screening program, enantioseparation of 86 racemic drugs was tested with hydroxypropyl-alpha-cyclodextrin as chiral solvating agent (csa). a total of 34 drugs out of 86 could be resolved in this straightforward approach. the number of experiments performed under identical conditions allows a correlation of the separation factors alpha(m) with the interaction strengths r-m. as shown for a subset of 23 drugs, the concentration of the csa is a crucial parameter for further optimization. (c) 1998 elsevier science b.v. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 类目[WOS] | biochemical research methods ; chemistry, analytical |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry |
| 关键词[WOS] | electrokinetic chromatography ; zone electrophoresis ; resolution ; micelles ; model |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000071668700015 |
| 公开日期 | 2015-11-10 |
| 源URL | [http://159.226.238.44/handle/321008/138176]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Univ Tubingen, Inst Organ Chem, D-72076 Tubingen, Germany 2.Inst Chem Phys, Dalian, Peoples R China |
| 推荐引用方式 GB/T 7714 | Koppenhoefer, B,Epperlein, U,Schlunk, R,et al. Separation of enantiomers of drugs by capillary electrophoresis - V. Hydroxypropyl-alpha-cyclodextrin as chiral solvating agent[J]. journal of chromatography a,1998,793(1):153-164. |
| APA | Koppenhoefer, B,Epperlein, U,Schlunk, R,Zhu, XF,&Lin, BC.(1998).Separation of enantiomers of drugs by capillary electrophoresis - V. Hydroxypropyl-alpha-cyclodextrin as chiral solvating agent.journal of chromatography a,793(1),153-164. |
| MLA | Koppenhoefer, B,et al."Separation of enantiomers of drugs by capillary electrophoresis - V. Hydroxypropyl-alpha-cyclodextrin as chiral solvating agent".journal of chromatography a 793.1(1998):153-164. |
入库方式： OAI收割
来源：大连化学物理研究所
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